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Western Blot (WB) (Western Blot analysis of PPP1R1A in 293T cell lysate using PPP1R1A Rabbit pAb at dilution 1/200)

Rabbit anti-Human, Rat PPP1R1A Polyclonal Antibody | anti-PPP1R1A antibody

PPP1R1A Rabbit pAb

Gene Names
PPP1R1A; I1; IPP1
Reactivity
Human, Rat
Applications
Western Blot, Immunohistochemistry
Purity
Affinity purified
Synonyms
PPP1R1A; Polyclonal Antibody; PPP1R1A Rabbit pAb; protein phosphatase 1 regulatory inhibitor subunit 1A; I1; IPP1; anti-PPP1R1A antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purified
Form/Format
pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration
0.72mg/ml (varies by lot)
Applicable Applications for anti-PPP1R1A antibody
Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P)
Application Notes
WB: 1:200-1:1000
IHC-P: 1:50-1:300
Immunogen
Fusion protein of human PPP1R1A
Conjugation
Unconjugated
Modification
Unmodified
Preparation and Storage
Store at 4 degree C for short term. Store at -20 degree C for long term. Avoid freeze/thaw cycle.

Western Blot (WB)

(Western Blot analysis of PPP1R1A in 293T cell lysate using PPP1R1A Rabbit pAb at dilution 1/200)

Western Blot (WB) (Western Blot analysis of PPP1R1A in 293T cell lysate using PPP1R1A Rabbit pAb at dilution 1/200)

Immunohistochemistry (IHC)

(Immunohistochemistry of PPP1R1A in paraffin-embedded Human tonsil tissue using PPP1R1A Rabbit pAb at dilution 1/50. Predicted cell location: Cytoplasm)

Immunohistochemistry (IHC) (Immunohistochemistry of PPP1R1A in paraffin-embedded Human tonsil tissue using PPP1R1A Rabbit pAb at dilution 1/50. Predicted cell location: Cytoplasm)
Related Product Information for anti-PPP1R1A antibody
Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
19,011 Da
NCBI Official Full Name
protein phosphatase 1 regulatory subunit 1A
NCBI Official Synonym Full Names
protein phosphatase 1, regulatory (inhibitor) subunit 1A
NCBI Official Symbol
PPP1R1A
NCBI Official Synonym Symbols
I1; IPP1
NCBI Protein Information
protein phosphatase 1 regulatory subunit 1A; I-1; IPP-1; inhibitor-1; protein phosphatase inhibitor 1; protein phosphatase inhibitor-1
UniProt Protein Name
Protein phosphatase 1 regulatory subunit 1A
UniProt Gene Name
PPP1R1A
UniProt Synonym Gene Names
IPP1; I-1; IPP-1
UniProt Entry Name
PPR1A_HUMAN

Uniprot Description

PPP1R1A: protein phosphatase 1, regulatory (inhibitor) subunit 1A. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases.

Protein type: Protein phosphatase, regulatory subunit; Inhibitor

Chromosomal Location of Human Ortholog: 12q13.2

Cellular Component: extracellular space; cytoplasm

Molecular Function: protein binding; type 1 serine/threonine specific protein phosphatase inhibitor activity

Biological Process: glycogen metabolic process; negative regulation of protein kinase activity

Research Articles on PPP1R1A

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Product Notes

The PPP1R1A ppp1r1a (Catalog #AAA4760388) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PPP1R1A Rabbit pAb reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PPP1R1A can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P). WB: 1:200-1:1000 IHC-P: 1:50-1:300. Researchers should empirically determine the suitability of the PPP1R1A ppp1r1a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PPP1R1A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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