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Western Blot (WB) (Anti-PPM1K Antibody at 1:1000 dilution + human heart lysateLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/10000 dilution.Predicted band size : 41 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Rabbit anti-Human PPM1K Polyclonal Antibody | anti-PPM1K antibody

PPM1K Antibody

Gene Names
PPM1K; BDP; PTMP; PP2Cm; MSUDMV; PP2Ckappa; UG0882E07
Reactivity
Human
Applications
Western Blot
Synonyms
PPM1K; Polyclonal Antibody; PPM1K Antibody; Purified Rabbit Polyclonal Antibody (Pab); anti-PPM1K antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Form/Format
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
Sequence Length
372
Applicable Applications for anti-PPM1K antibody
Western Blot (WB)
Application Notes
WB ~~1:1000
Antigen Source
Human
Antigen Type
A Synthesized Peptide
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(Anti-PPM1K Antibody at 1:1000 dilution + human heart lysateLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/10000 dilution.Predicted band size : 41 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Western Blot (WB) (Anti-PPM1K Antibody at 1:1000 dilution + human heart lysateLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/10000 dilution.Predicted band size : 41 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Related Product Information for anti-PPM1K antibody
Regulates the mitochondrial permeability transition pore and is essential for cellular survival and development.
Product Categories/Family for anti-PPM1K antibody
References
Lu G.,et al.Genes Dev. 21:784-796(2007). Mao Y.,et al.Submitted (OCT-2002) to the EMBL/GenBank/DDBJ databases. Joshi M.A.,et al.Biochem. Biophys. Res. Commun. 356:38-44(2007). Xu J.,et al.Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases. Ota T.,et al.Nat. Genet. 36:40-45(2004).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
40997
NCBI Official Full Name
protein phosphatase 1K, mitochondrial
NCBI Official Synonym Full Names
protein phosphatase, Mg2+/Mn2+ dependent 1K
NCBI Official Symbol
PPM1K
NCBI Official Synonym Symbols
BDP; PTMP; PP2Cm; MSUDMV; PP2Ckappa; UG0882E07
NCBI Protein Information
protein phosphatase 1K, mitochondrial
UniProt Protein Name
Protein phosphatase 1K, mitochondrial
Protein Family
UniProt Gene Name
PPM1K
UniProt Synonym Gene Names
PP2CM; PTMP; PP2C-kappa
UniProt Entry Name
PPM1K_HUMAN

NCBI Description

This gene encodes a member of the PPM family of Mn2+/Mg2+-dependent protein phosphatases. The encoded protein, essential for cell survival and development, is targeted to the mitochondria where it plays a key role in regulation of the mitochondrial permeability transition pore. [provided by RefSeq, Sep 2012]

Uniprot Description

PPM1K: Regulates the mitochondrial permeability transition pore and is essential for cellular survival and development. Belongs to the PP2C family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Protein phosphatase, Ser/Thr (non-receptor); Motility/polarity/chemotaxis; Mitochondrial; EC 3.1.3.16

Chromosomal Location of Human Ortholog: 4q22.1

Cellular Component: mitochondrial matrix

Molecular Function: protein binding; metal ion binding; protein serine/threonine phosphatase activity

Biological Process: protein amino acid dephosphorylation

Disease: Maple Syrup Urine Disease, Mild Variant

Research Articles on PPM1K

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Product Notes

The PPM1K ppm1k (Catalog #AAA9216484) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PPM1K Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PPM1K can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB ~~1:1000. Researchers should empirically determine the suitability of the PPM1K ppm1k for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PPM1K, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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