Western Blot (WB)
(Western blot analysis of POLE2 using LOVO whole cell lysates)
Rabbit anti-Human POLE2 Polyclonal Antibody | anti-POLE2 antibody
POLE2 Antibody
Gene Names
POLE2; DPE2
Reactivity
Human
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
POLE2; Polyclonal Antibody; POLE2 Antibody; DNA polymerase epsilon subunit 2; DNA polymerase epsilon subunit B; DNA polymerase II subunit 2; DPE 2; DPE2; DPOE2_HUMAN; POLE 2; Polymerase (DNA directed) epsilon 2 (p59 subunit); Polymerase (DNA directed) epsilon 2; polymerase (DNA directed); epsilon 2; accessory subunit; Polymerase; DNA; epsilon-2; anti-POLE2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
POLE2 antibody detects endogenous levels of total POLE2
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
501
Applicable Applications for anti-POLE2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:1000-3000
Immunogen
A synthesized peptide derived from human POLE2
Subcellular Location
Nucleus.
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Western Blot (WB)
(Western blot analysis of POLE2 using LOVO whole cell lysates)
Western Blot (WB)
(Western blot analysis of POLE2 using LOVO whole cell lysates)
Related Product Information for anti-POLE2 antibody
Function: Participates in DNA repair and in chromosomal DNA replication.
Subunit Structure: Component of the epsilon DNA polymerase complex consisting of four subunits: POLE, POLE2, POLE3 and POLE4.
Similarity: Belongs to the DNA polymerase epsilon subunit B family.
Subunit Structure: Component of the epsilon DNA polymerase complex consisting of four subunits: POLE, POLE2, POLE3 and POLE4.
Similarity: Belongs to the DNA polymerase epsilon subunit B family.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Observed: 60 kDa
Predicted: 60 kDa
Predicted: 60 kDa
NCBI Official Full Name
DNA polymerase epsilon subunit 2 isoform 2
NCBI Official Synonym Full Names
DNA polymerase epsilon 2, accessory subunit
NCBI Official Symbol
POLE2
NCBI Official Synonym Symbols
DPE2
NCBI Protein Information
DNA polymerase epsilon subunit 2
UniProt Protein Name
DNA polymerase epsilon subunit 2
Protein Family
UniProt Gene Name
POLE2
UniProt Synonym Gene Names
DPE2
NCBI Description
DNA polymerase epsilon, which is involved in DNA repair and replication, is composed of a large catalytic subunit and a small accessory subunit. The protein encoded by this gene represents the small subunit (B). Defects in this gene have been linked to colorectal cancer and to combined immunodeficiency. [provided by RefSeq, Jan 2017]
Uniprot Description
Participates in DNA repair and in chromosomal DNA replication.
Research Articles on POLE2
Similar Products
Product Notes
The POLE2 pole2 (Catalog #AAA9609763) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The POLE2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's POLE2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:1000-3000. Researchers should empirically determine the suitability of the POLE2 pole2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "POLE2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
