Western Blot (WB)
(WB Suggested Anti-PNLIP Antibody Titration: 1.25ug/mlPositive Control: Jurkat cell lysate)
Rabbit PNLIP Polyclonal Antibody | anti-PNLIP antibody
PNLIP antibody - C-terminal region
Western Blot (WB)
(WB Suggested Anti-PNLIP Antibody Titration: 1.25ug/mlPositive Control: Jurkat cell lysate)
Western Blot (WB)
(WB Suggested Anti-PNLIP Antibody Titration: 1.25ug/mlPositive Control: Jurkat cell lysate)
Target Description: PNLIP is a member of the lipase gene family. It encodes a carboxyl esterase that hydrolyzes insoluble, emulsified triglycerides, and is essential for the efficient digestion of dietary fats. This gene is expressed specifically in the pancreas.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the lipase family of proteins. The encoded enzyme is secreted by the pancreas and hydrolyzes triglycerides in the small intestine, and is essential for the efficient digestion of dietary fats. Inhibition of the encoded enzyme may prevent high-fat diet-induced obesity in mice and result in weight loss in human patients with obesity. Mutations in this gene cause congenital pancreatic lipase deficiency, a rare disorder characterized by steatorrhea. [provided by RefSeq, Jul 2016]
Uniprot Description
PNLIP: a member of the lipase gene family. It encodes a carboxyl esterase that hydrolyzes insoluble, emulsified triglycerides, and is essential for the efficient digestion of dietary fats. expressed specifically in the pancreas. [provided by RefSeq, Jul 2008]
Protein type: EC 3.1.1.3; Lipid Metabolism - glycerolipid; Secreted; Secreted, signal peptide; Hydrolase
Chromosomal Location of Human Ortholog: 10q26.1
Cellular Component: extracellular region
Molecular Function: triacylglycerol lipase activity; metal ion binding
Biological Process: phototransduction, visible light; cholesterol absorption; retinoid metabolic process; lipid catabolic process; lipid digestion
Disease: Pancreatic Lipase Deficiency
Research Articles on PNLIP
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Product Notes
The PNLIP pnlip (Catalog #AAA3201751) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PNLIP antibody - C-terminal region reacts with Cow, Dog, Horse, Human, Pig and may cross-react with other species as described in the data sheet. AAA Biotech's PNLIP can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the PNLIP pnlip for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: SGKKVTGHIL VSLFGNKGNS KQYEIFKGTL KPDSTHSNEF DSDVDVGDLQ. It is sometimes possible for the material contained within the vial of "PNLIP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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