Western Blot (WB)
(Western blot analysis of PMPCB Antibody (N-term) in mouse kidney tissue lysates (35ug/lane). PMPCB (arrow) was detected using the purified Pab.)
Rabbit anti-Human, mouse PMPCB Polyclonal Antibody | anti-PMPCB antibody
PMPCB Antibody (N-term)
Western Blot (WB)
(Western blot analysis of PMPCB Antibody (N-term) in mouse kidney tissue lysates (35ug/lane). PMPCB (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of PMPCB Antibody (N-term) in mouse kidney tissue lysates (35ug/lane). PMPCB (arrow) was detected using the purified Pab.)
Immunohistochemistry (IHC)
(PMPCB Antibody (N-term) IHC analysis in formalin fixed and paraffin embedded mouse kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PMPCB Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(PMPCB Antibody (N-term) IHC analysis in formalin fixed and paraffin embedded mouse kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PMPCB Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Flow Cytometry (FC/FACS)
(PMPCB Antibody (N-term) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Flow Cytometry (FC/FACS)
(PMPCB Antibody (N-term) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Schwer, B., et al. J. Cell Biol. 158(4):647-657(2002)
Nagao, Y., et al. J. Biol. Chem. 275(44):34552-34556(2000)
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the peptidase M16 family and encodes a protein with a zinc-binding motif. This protein is located in the mitochondrial matrix and catalyzes the cleavage of the leader peptides of precursor proteins newly imported into the mitochondria, though it only functions as part of a heterodimeric complex. [provided by RefSeq, Jul 2008]
Uniprot Description
PMPCB: Cleaves presequences (transit peptides) from mitochondrial protein precursors. Belongs to the peptidase M16 family.
Protein type: Protease; Mitochondrial; EC 3.4.24.64
Chromosomal Location of Human Ortholog: 7q22.1
Cellular Component: mitochondrial matrix; mitochondrial inner membrane
Molecular Function: metal ion binding; metalloendopeptidase activity
Biological Process: cellular protein metabolic process; proteolysis; protein targeting to mitochondrion
Research Articles on PMPCB
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Product Notes
The PMPCB pmpcb (Catalog #AAA9208034) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 18-46. The PMPCB Antibody (N-term) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's PMPCB can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS). WB~~1:1000. Researchers should empirically determine the suitability of the PMPCB pmpcb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PMPCB, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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