Western Blot (WB)
(PLXNC1 Antibody (C-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the PLXNC1 antibody detected the PLXNC1 protein (arrow).)
Rabbit anti-Mouse PLXNC1 Polyclonal Antibody | anti-PLXNC1 antibody
PLXNC1 Antibody (C-term)
Western Blot (WB)
(PLXNC1 Antibody (C-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the PLXNC1 antibody detected the PLXNC1 protein (arrow).)
Western Blot (WB)
(PLXNC1 Antibody (C-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the PLXNC1 antibody detected the PLXNC1 protein (arrow).)
Immunohistochemistry (IHC)
(PLXNC1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human cerebellum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PLXNC1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(PLXNC1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human cerebellum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PLXNC1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Lazova, R., et al. Am J Dermatopathol 31(2):177-181(2009)
Scott, G.A., et al. J. Invest. Dermatol. 129(4):954-963(2009)
Scott, G.A., et al. J. Invest. Dermatol. 128(1):151-161(2008)
Li, Y., et al. PLoS ONE 3 (7), E2707 (2008) :
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the plexin family. Plexins are transmembrane receptors for semaphorins, a large family of proteins that regulate axon guidance, cell motility and migration, and the immune response. The encoded protein and its ligand regulate melanocyte adhesion, and viral semaphorins may modulate the immune response by binding to this receptor. The encoded protein may be a tumor suppressor protein for melanoma. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jan 2011]
Uniprot Description
PLXNC1: Receptor for SEMA7A, for smallpox semaphorin A39R, vaccinia virus semaphorin A39R and for herpesvirus Sema protein. Binding of semaphorins triggers cellular responses leading to the rearrangement of the cytoskeleton and to secretion of IL6 and IL8. Belongs to the plexin family.
Protein type: Motility/polarity/chemotaxis; Cell adhesion; Membrane protein, integral
Chromosomal Location of Human Ortholog: 12q23.3
Cellular Component: membrane; plasma membrane; integral to membrane; intracellular
Molecular Function: protein binding; receptor activity; receptor binding
Biological Process: axon guidance; signal transduction; cell adhesion
Research Articles on PLXNC1
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Product Notes
The PLXNC1 plxnc1 (Catalog #AAA9209219) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1025-1054. The PLXNC1 Antibody (C-term) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's PLXNC1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the PLXNC1 plxnc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PLXNC1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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