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Testing Data

Rabbit PLD3 Polyclonal Antibody | anti-PLD3 antibody

Anti-PLD3 Antibody

Gene Names
PLD3; AD19; HUK4; HU-K4
Reactivity
Human. Predicted: Mouse, Rat.
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Affinity purified
Synonyms
PLD3; Polyclonal Antibody; Anti-PLD3 Antibody; anti-PLD3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human. Predicted: Mouse, Rat.
Clonality
Polyclonal
Purity/Purification
Affinity purified
Form/Format
Liquid
Concentration
100ug/100ul (varies by lot)
Sequence Length
490
Applicable Applications for anti-PLD3 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
ELISA titer: 1:20,000-1:80,000
Western blot analysis: 1:1,000-1:2,000
Immunohistochemistry: 1:100-1:500
Optimal dilutions/concentrations should be determined by the end user.
Storage Buffer
PBS, pH 7.4 with 0.02% Sodium Azide
Immunogen
Rabbit polyclonal PLD3 (1) antibody was raised against a recombinate human PLD3 protein 162-439aa (BC036327).
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

Testing Data

Testing Data
References
(1) Zhang,J., Chen,S., Zhang,S. et al. [Over-expression of phospholipase D3 inhibits Akt phosphorylation in C2C12 myoblasts]. Sheng Wu Gong Cheng Xue Bao 25 (10), 1524-1531 (2009).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
54,705 Da
NCBI Official Full Name
phospholipase D3
NCBI Official Synonym Full Names
phospholipase D family, member 3
NCBI Official Symbol
PLD3
NCBI Official Synonym Symbols
AD19; HUK4; HU-K4
NCBI Protein Information
phospholipase D3; choline phosphatase 3; hindIII K4L homolog; phosphatidylcholine-hydrolyzing phospholipase D3
UniProt Protein Name
Phospholipase D3
Protein Family
UniProt Gene Name
PLD3
UniProt Entry Name
PLD3_HUMAN

NCBI Description

This gene encodes a member of the phospholipase D (PLD) family of enzymes that catalyze the hydrolysis of membrane phospholipids. The encoded protein is a single-pass type II membrane protein and contains two PLD phosphodiesterase domains. This protein influences processing of amyloid-beta precursor protein. Mutations in this gene are associated with Alzheimer disease risk. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Apr 2014]

Uniprot Description

PLD3: Belongs to the phospholipase D family.

Protein type: Endoplasmic reticulum; EC 3.1.4.4; Membrane protein, integral; Phospholipase

Chromosomal Location of Human Ortholog: 19q13.2

Cellular Component: endoplasmic reticulum membrane; integral to membrane

Molecular Function: protein binding; phospholipase D activity

Biological Process: phosphatidylglycerol biosynthetic process; phospholipid metabolic process; glycerophospholipid biosynthetic process; lipid catabolic process

Disease: Alzheimer Disease 19

Research Articles on PLD3

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Product Notes

The PLD3 pld3 (Catalog #AAA416193) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-PLD3 Antibody reacts with Human. Predicted: Mouse, Rat. and may cross-react with other species as described in the data sheet. AAA Biotech's PLD3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). ELISA titer: 1:20,000-1:80,000 Western blot analysis: 1:1,000-1:2,000 Immunohistochemistry: 1:100-1:500 Optimal dilutions/concentrations should be determined by the end user. Researchers should empirically determine the suitability of the PLD3 pld3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PLD3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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