Rabbit anti-Mouse, Rat PLCL1 Polyclonal Antibody | anti-PLCL1 antibody
PLCL1 Polyclonal Antibody
NCBI and Uniprot Product Information
Uniprot Description
PLCL1: a protein closely related to phospholipase C-d1 (PLC-d1) but catalytically inactive. First identified as a novel inositol 1,4,5-trisphosphate binding protein. Has a number of binding partners including protein phosphatase (PP1 and 2A), GABA(A) receptor associated protein, and the beta subunits of GABA(A) receptors, in addition to inositol 1,4,5-trisphosphate. Plays an important role in controlling the dynamics of GABA(A) receptor phosphorylation through PP1 binding and, therefore, the efficacy of synaptic inhibition mediated by these receptors.
Protein type: Phospholipase
Chromosomal Location of Human Ortholog: 2q33
Cellular Component: cytoplasm; plasma membrane
Molecular Function: signal transducer activity; GABA receptor binding; phosphoinositide phospholipase C activity; phospholipase C activity
Biological Process: regulation of peptidyl-serine phosphorylation; lipid metabolic process; regulation of synaptic transmission, GABAergic; gamma-aminobutyric acid signaling pathway
Research Articles on PLCL1
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Product Notes
The PLCL1 plcl1 (Catalog #AAA8569985) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PLCL1 Polyclonal Antibody reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PLCL1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:200-1:2000. Researchers should empirically determine the suitability of the PLCL1 plcl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PLCL1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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