Testing Data
(Western blot analysis of extracts from HepG2 and 293 cells using PKM1/2 antibody.)
Rabbit PKM2 Polyclonal Antibody | anti-PKM2 antibody
PKM2 antibody
Applications
Western Blot
Purity
Purified by immunoaffinity chromatography.
Synonyms
PKM2; Polyclonal Antibody; PKM2 antibody; Rabbit polyclonal PKM2 antibody; Polyclonal PKM2 antibody; Anti-PKM2 antibody; PK2 antibody; PKM 2; PKM antibody; Pyruvate kinase muscle antibody; Pyruvate kinase isozymes M1/M2 antibody; THBP1 antibody; CTHBP antibody; Pyruvate kinase 2/3 antibody; M2-PK antibody; p58 antibody; PKM-2; Tumor M2-PK antibody; PKM 2 antibody; PKM-2 antibody; TCB antibody; OPA interacting protein 3 antibody; Thyroid hormone binding protein cytosolic antibody; pyruvate kinase antibody; muscle isoform M2 OIP3 antibody; PK3 antibody; Cytosolic thyroid hormone binding protein antibody; anti-PKM2 antibody
Host
Rabbit
Clonality
Polyclonal
Purity/Purification
Purified by immunoaffinity chromatography.
Form/Format
Liquid form in PBS buffer (no MG2+ or Ca2+), pH 7.4, 150 mm NaCl,0.02% sodium azide and 50% glycerol.
Concentration
1 mg/ml (varies by lot)
Applicable Applications for anti-PKM2 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:1000
Immunogen
PKM2 antibody was raised in Rabbit using the peptide sequence around aa 36~40(D-S-P-P-I) derived from Human PKM2 as the immunogen.
Cross-Reactivity
Human
Preparation and Storage
Store at 4 degree C for short term storage.
Aliquot and store at-20 degree C for long term storage.
Avoid repeated freeze/thaw cycles.
Aliquot and store at-20 degree C for long term storage.
Avoid repeated freeze/thaw cycles.
Testing Data
(Western blot analysis of extracts from HepG2 and 293 cells using PKM1/2 antibody.)
Testing Data
(Western blot analysis of extracts from HepG2 and 293 cells using PKM1/2 antibody.)
Related Product Information for anti-PKM2 antibody
PKM2 (pyruvate kinase M2), its association with phospho-tyrosine (pTyr) motifs, enables cells to use predominantly aerobic glycolysis instead of oxidative phosphorylation. Also this change may benefit cancer cells by enabling them to redirect glycolytic metabolites away from oxidation and energy production and, instead, toward anabolic processes and biosynthesis. PKM2-mediated generation of the aerobic glycolytic phenotype, although wasteful in terms of glucose consumption and waste generation, could provide a variety of advantages for cancerous cells. In addition nuclear translocation of the tumor marker pyruvate kinase M2 induces programmed cell death.
Product Categories/Family for anti-PKM2 antibody
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Product Notes
The PKM2 (Catalog #AAA5309828) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's PKM2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the PKM2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PKM2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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