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Western Blot (WB) (Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane 1-6: Rat brain tissue, Human cerebrum tissue, Human fetal brain tissue, Hela cell, Human breast cancer tissue, Jurkat cell lysates, Primary antibody: 124812(PITPNB Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds)

Rabbit anti-Human, Rat PITPNB Polyclonal Antibody | anti-PITPNB antibody

PITPNB Rabbit pAb

Gene Names
PITPNB; VIB1B; PtdInsTP; PI-TP-beta
Reactivity
Human, Rat
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Affinity purified
Synonyms
PITPNB; Polyclonal Antibody; PITPNB Rabbit pAb; VIB1B; PtdInsTP; PI-TP-beta; anti-PITPNB antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Rat
Clonality
Polyclonal
Isotype
Rabbit IgG
Purity/Purification
Affinity purified
Form/Format
-20 degree C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Applicable Applications for anti-PITPNB antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P)
Application Notes
WB: 1:500-1:2000
Immunogen
Fusion protein of human PITPNB
Conjugation
Unconjugated
Molecular Function
This gene encodes a cytoplasmic protein that catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes. This transfer activity is required for COPI complex-mediated retrograde transport from the Golgi apparatus to the endoplasmic reticulum. Alternative splicing of this gene results in multiple transcript variants.
Modification
Unmodified
Cell Position
Cytoplasm, Golgi apparatus
Preparation and Storage
Store at 4 degree C for short term. Store at -20 degree C for long term. Avoid freeze/thaw cycle.

Western Blot (WB)

(Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane 1-6: Rat brain tissue, Human cerebrum tissue, Human fetal brain tissue, Hela cell, Human breast cancer tissue, Jurkat cell lysates, Primary antibody: 124812(PITPNB Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds)

Western Blot (WB) (Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane 1-6: Rat brain tissue, Human cerebrum tissue, Human fetal brain tissue, Hela cell, Human breast cancer tissue, Jurkat cell lysates, Primary antibody: 124812(PITPNB Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds)

Immunohistochemistry (IHC)

(The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using 124812(PITPNB Antibody) at dilution 1/25. (Original magnification: ×200))

Immunohistochemistry (IHC) (The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using 124812(PITPNB Antibody) at dilution 1/25. (Original magnification: ×200))
Product Categories/Family for anti-PITPNB antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
31,700 Da
NCBI Official Full Name
Homo sapiens phosphatidylinositol transfer protein, beta, mRNA
NCBI Official Synonym Full Names
phosphatidylinositol transfer protein, beta
NCBI Official Symbol
PITPNB
NCBI Official Synonym Symbols
VIB1B; PtdInsTP; PI-TP-beta
NCBI Protein Information
phosphatidylinositol transfer protein beta isoform; PtdIns transfer protein beta; phosphotidylinositol transfer protein, beta
UniProt Protein Name
Phosphatidylinositol transfer protein beta isoform
UniProt Gene Name
PITPNB
UniProt Synonym Gene Names
PI-TP-beta; PtdIns transfer protein beta
UniProt Entry Name
PIPNB_HUMAN

NCBI Description

This gene encodes a cytoplasmic protein that catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes. This transfer activity is required for COPI complex-mediated retrograde transport from the Golgi apparatus to the endoplasmic reticulum. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2013]

Uniprot Description

PITPNB: transfers phosphatidylinositol, phosphatidylcholine and sphingomyelin between membrane bilayers. Associates mainly with the trans-Golgi network. Ser-261 is constitutively phosphorylated.

Protein type: Lipid-binding

Chromosomal Location of Human Ortholog: 22q12.1

Cellular Component: Golgi membrane; endoplasmic reticulum membrane

Molecular Function: lipid binding

Biological Process: in utero embryonic development; phospholipid metabolic process; glycerophospholipid biosynthetic process; phospholipid transport; lipid metabolic process

Research Articles on PITPNB

Similar Products

Product Notes

The PITPNB pitpnb (Catalog #AAA4754623) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PITPNB Rabbit pAb reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PITPNB can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the PITPNB pitpnb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PITPNB, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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