Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human colon using MBS7602680 (PIGZ antibody) at dilution of 1:100)
Rabbit PIGZ Polyclonal Antibody | anti-PIGZ antibody
PIGZ Rabbit Polyclonal
Purity: > or = 95% as determined by SDS-PAGE
Purity: > or = 95% as determined by SDS-PAGE
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human colon using MBS7602680 (PIGZ antibody) at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human colon using MBS7602680 (PIGZ antibody) at dilution of 1:100)
Immunofluorescence (IF)
(Immunofluorescent analysis of (-20 degree C Ethanol) fixed HepG2 cells using MBS7602680 (PIGZ antibody) at dilution of 1:50 and Alexa Fluor 488-congugated Goat Anti-Rabbit IgG (H+L))
Immunofluorescence (IF)
(Immunofluorescent analysis of (-20 degree C Ethanol) fixed HepG2 cells using MBS7602680 (PIGZ antibody) at dilution of 1:50 and Alexa Fluor 488-congugated Goat Anti-Rabbit IgG (H+L))
Western Blot (WB)
(human brain tissue were subjected to SDS PAGE followed by western blot with MBS7602680 (PIGZ antibody) at dilution of 1:500)
Western Blot (WB)
(human brain tissue were subjected to SDS PAGE followed by western blot with MBS7602680 (PIGZ antibody) at dilution of 1:500)
NCBI and Uniprot Product Information
NCBI Description
The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on many blood cells that serves to anchor proteins to the cell surface. This gene encodes a protein that is localized to the endoplasmic reticulum, and is involved in GPI anchor biosynthesis. As shown for the yeast homolog, which is a member of a family of dolichol-phosphate-mannose (Dol-P-Man)-dependent mannosyltransferases, this protein can also add a side-branching fourth mannose to GPI precursors during the assembly of GPI anchors. [provided by RefSeq, Jul 2008]
Uniprot Description
PIGZ: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers a fourth mannose to some trimannosyl-GPIs during GPI precursor assembly. The presence of a fourth mannose in GPI is facultative and only scarcely detected, suggesting that it only exists in some tissues. Belongs to the glycosyltransferase 22 family. PIGZ subfamily.
Protein type: Glycan Metabolism - glycosylphosphatidylinositol (GPI)-anchor biosynthesis; EC 2.4.1.-; Transferase; Membrane protein, multi-pass; Membrane protein, integral; Endoplasmic reticulum
Chromosomal Location of Human Ortholog: 3q29
Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane
Molecular Function: alpha-1,2-mannosyltransferase activity; mannosyltransferase activity
Biological Process: GPI anchor biosynthetic process
Research Articles on PIGZ
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Product Notes
The PIGZ pigz (Catalog #AAA7602680) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PIGZ Rabbit Polyclonal reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PIGZ can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). WB: 1:1000-1:4000; IHC: 1:20-1:200; IF: 1:50-1:500. Researchers should empirically determine the suitability of the PIGZ pigz for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PIGZ, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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