Rabbit PIBF Polyclonal Antibody | anti-PIBF1 antibody

Anti-PIBF Antibody

Cat. Num. AAA8245369

• Gene Names: PIBF1; PIBF; CEP90; C13orf24
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, Immunohistochemistry
• Purity: The antibody was purified by immunogen affinity chromatography.
• Synonyms: PIBF; Polyclonal Antibody; Anti-PIBF Antibody; C13orf24; Progesterone-induced-blocking factor 1; anti-PIBF1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Specificity: Recognizes endogenous levels of PIBF protein.
• Purity/Purification: The antibody was purified by immunogen affinity chromatography.
• Form/Format: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
• Sequence Length: 757

• Applicable Applications for anti-PIBF1 antibody: Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: WB: 1/500 - 1/1000; IHC: 1/50 - 1/100
• Immunogen: KLH-conjugated synthetic peptide of human PIBF
• Preparation and Storage: Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of PIBF expression in mouse heart (A) whole cell lysates.)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of PIBF staining in human colon cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.)

Related Product Information for anti-PIBF1 antibody

Rabbit polyclonal antibody to PIBF

NCBI and Uniprot Product Information

• NCBI GI #: 55769583
• NCBI GeneID: 10464
• NCBI Accession #: NP_006337.2
• NCBI GenBank Nucleotide #: NM_006346.2
• UniProt Accession #: Q8WXW3; O95664; Q6U9V2; Q6UG50; Q86V07; Q96SF4
• Molecular Weight: 35,071 Da
• NCBI Official Full Name: progesterone-induced-blocking factor 1
• NCBI Official Synonym Full Names: progesterone immunomodulatory binding factor 1
• NCBI Official Symbol: PIBF1
• NCBI Official Synonym Symbols: PIBF; CEP90; C13orf24
• NCBI Protein Information: progesterone-induced-blocking factor 1
• UniProt Protein Name: Progesterone-induced-blocking factor 1
• Protein Family: Progesterone-induced-blocking factor
• UniProt Gene Name: PIBF1
• UniProt Synonym Gene Names: C13orf24; PIBF; PIBF; CEP90
• UniProt Entry Name: PIBF1_HUMAN

Uniprot Description

PIBF1: Mediator of progesterone that by acting on the phospholipase A2 enzyme interferes with arachidonic acid metabolism, induces a Th2 biased immune response, and by controlling NK activity exerts an anti-abortive effect. 3 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 13q22.1

Cellular Component: centrosome; extracellular space; nucleus

Molecular Function: interleukin-4 receptor binding; protein binding

Biological Process: immune system process; mitotic metaphase plate congression; negative regulation of interleukin-12 production; negative regulation of natural killer cell activation; negative regulation of prostaglandin biosynthetic process; negative regulation of tyrosine phosphorylation of Stat4 protein; positive regulation of interleukin-10 production; positive regulation of tyrosine phosphorylation of Stat6 protein; sensory cilium biogenesis