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Western Blot (WB) (human placenta tissue were subjected to SDS PAGE followed by western blot with MBS7602634 (phospho (409/410) -TDP43 antibody) at dilution of 1:1000)

Rabbit anti-Human, Mouse phospho(409/410)-TDP43 Polyclonal Antibody | anti-TDP43 antibody

phospho(409/410)-TDP43 Rabbit Polyclonal

Reactivity
Human, Mouse
Applications
ELISA, Western Blot
Purity
Purity: >=95% as determined by SDS-PAGE
Purification: Immunogen affinity purified
Synonyms
phospho(409/410)-TDP43; Polyclonal Antibody; phospho(409/410)-TDP43 Rabbit Polyclonal; phospho TDP43; TARDBP; TDP43; anti-TDP43 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purity: >=95% as determined by SDS-PAGE
Purification: Immunogen affinity purified
Form/Format
Liquid; PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freezez/thaw cycles.)
Applicable Applications for anti-TDP43 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
WB: 1:500 - 1:2000
Immunogen
TAR DNA binding protein
Preparation and Storage
Store -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Western Blot (WB)

(human placenta tissue were subjected to SDS PAGE followed by western blot with MBS7602634 (phospho (409/410) -TDP43 antibody) at dilution of 1:1000)

Western Blot (WB) (human placenta tissue were subjected to SDS PAGE followed by western blot with MBS7602634 (phospho (409/410) -TDP43 antibody) at dilution of 1:1000)
Related Product Information for anti-TDP43 antibody
TDP-43 is a 414 amino acid (aa) nuclear DNA and RNA-binding protein which regulates transcription and splicing. TDP-43 is aberrantly expressed in most forms of amylotrophic lateral sclerosis and frontotemporal lobar degeneration. In these cases it is absent from the nucleus and accumulates, along with a truncated 25kDa form, in ubiquitin-containing inclusion bodies. In pathological tissues, TDP-43 is highly phosphorylated and Ser409/410 is the main phosphorylation site. Among the TDP-43 protein fragments, the 25kDa fragment is also highly phosphorylated and widely believed to be pathogenic. This antibody is a rabbit polyclonal antibody recognizing TDP-43 only when phosphorylated at 409/410. This antibody detects phosphorylated forms of TDP-43 as well as the cleavage product of 25 kDa.

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Product Notes

The TDP43 (Catalog #AAA7602634) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The phospho(409/410)-TDP43 Rabbit Polyclonal reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's phospho(409/410)-TDP43 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). WB: 1:500 - 1:2000. Researchers should empirically determine the suitability of the TDP43 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "phospho(409/410)-TDP43, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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