Dot Blot (DB)
(Dot blot analysis of mouse TSC2 Antibody (Phospho S1096) Phospho-specific Pab on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml.)
Rabbit Phospho-mouse TSC2 (S1096) Polyclonal Antibody | anti-Tsc2 antibody
Phospho-mouse TSC2 (S1096) Antibody
Dot Blot (DB)
(Dot blot analysis of mouse TSC2 Antibody (Phospho S1096) Phospho-specific Pab on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml.)
Dot Blot (DB)
(Dot blot analysis of mouse TSC2 Antibody (Phospho S1096) Phospho-specific Pab on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml.)
NCBI and Uniprot Product Information
Uniprot Description
TSC2: a product of the tumor suppressor gene TSC2. Tuberin and Hamartin (TSC1) form a tumor suppressor heterodimer that inhibits the mTOR nutrient signaling input. TSC1/TSC2 targets the small G protein Rheb, a novel mediator of the nutrient signaling input to mTOR. Functions as a Rheb GTPase activating protein (GAP). Four alternatively spliced isoforms have been described.
Protein type: GAPs, misc.; Tumor suppressor; Nuclear receptor co-regulator; Cell cycle regulation; GAPs
Cellular Component: neuron projection; protein complex; intracellular membrane-bound organelle; cell; dendrite; caveola; cytosol; lipid raft; TSC1-TSC2 complex; growth cone; cytoskeleton; cell soma; membrane; perinuclear region of cytoplasm; cytoplasm; intracellular
Molecular Function: protein binding; protein homodimerization activity; protein heterodimerization activity; GTPase activator activity; phosphatase binding
Biological Process: negative regulation of MAP kinase activity; phosphoinositide 3-kinase cascade; regulation of insulin receptor signaling pathway; negative regulation of Wnt receptor signaling pathway; regulation of cell cycle; protein heterooligomerization; heart development; negative regulation of insulin receptor signaling pathway; negative regulation of cell size; signal transduction; negative regulation of cell proliferation; protein localization; establishment of protein localization; positive chemotaxis; cell projection organization and biogenesis; protein import into nucleus; regulation of endocytosis; protein kinase B signaling cascade; acute-phase response; protein homooligomerization; negative regulation of epithelial cell proliferation; negative regulation of TOR signaling pathway; negative regulation of protein kinase B signaling cascade; regulation of small GTPase mediated signal transduction; cellular response to insulin stimulus; insulin-like growth factor receptor signaling pathway; glucose import; neural tube closure; response to hypoxia; negative regulation of protein kinase activity; positive regulation of transcription from RNA polymerase II promoter; positive regulation of GTPase activity; negative regulation of phosphoinositide 3-kinase cascade
Research Articles on Tsc2
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Product Notes
The Tsc2 tsc2 (Catalog #AAA9214417) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Phospho-mouse TSC2 (S1096) Antibody reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Phospho-mouse TSC2 (S1096) can be used in a range of immunoassay formats including, but not limited to, Dot Blot (DB), ELISA (EIA). DB~~1:500. Researchers should empirically determine the suitability of the Tsc2 tsc2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Phospho-mouse TSC2 (S1096), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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