Rabbit anti-Mouse, Human Phospho-ERK8 Polyclonal Antibody | anti-MAPK15 antibody

Phospho-ERK8 (Thr175+Tyr177) Antibody

Cat. Num. AAA847590

• Gene Names: MAPK15; ERK7; ERK8
• Reactivity: Mouse, Human
• Applications: Immunofluorescence, Immunocytochemistry, Western Blot, ELISA
• Purity: Affinity purification
• Synonyms: Phospho-ERK8; Polyclonal Antibody; Phospho-ERK8 (Thr175+Tyr177) Antibody; ERK-7; ERK-8; ERK7; ERK8; Extracellular regulated kinase 8 delta; Extracellular signal regulated kinase 8; Extracellular signal-regulated kinase 7; Extracellular signal-regulated kinase 8; MAP kinase 15; MAPK 15; Mapk15; Mitogen activated protein kinase 15; Mitogen-activated protein kinase 15; MK15_HUMAN; anti-MAPK15 antibody

• Host: Rabbit
• Reactivity: Mouse, Human
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Specificity: Polyclonal antibody to detect Phospho-ERK8 (Thr175+Tyr177)
• Purity/Purification: Affinity purification
• Form/Format: Colorless liquid. In phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: 1mg/ml (varies by lot)

• Applicable Applications for anti-MAPK15 antibody: Immunofluorescence (IF), Immunocytochemistry (ICC), Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:500-1:2000; IF: 1:100-1:500; ICC: 1:100-1:500; ELISA (peptide): 1:20,000-1:40,000
• Immunogen: A synthesized peptide derived from human ERK8 around the phosphorylation site of Threonine 175 and Tyrosine 177
• Preparation and Storage: Store at -20 degree C; The antibody solution should be gently mixed before use.; Shelf life: ~12 months

ELISA (EIA)

Immunocytochemistry/Immunofluorescence (ICC/IF))

Western Blot (WB)

Related Product Information for anti-MAPK15 antibody

ERK7 is phosphorylates MBP in vitro. Interacts with CSK/cSrc, ABL1 and RET. 3 isoforms of the human protein are produced by alternative splicing.

Product Categories/Family for anti-MAPK15 antibody

Antibodies & Supporting Tools; Phospho Specific Antibodies; Primary Antibodies (A-Z)

NCBI and Uniprot Product Information

• NCBI GI #: 95147356
• NCBI GeneID: 225689
• NCBI Accession #: NP_620590.2
• NCBI GenBank Nucleotide #: NM_139021.2
• UniProt Accession #: Q8TD08; Q2TCF9; Q8N362
• Molecular Weight: 59,832 Da
• NCBI Official Full Name: mitogen-activated protein kinase 15
• NCBI Official Synonym Full Names: mitogen-activated protein kinase 15
• NCBI Official Symbol: MAPK15
• NCBI Official Synonym Symbols: ERK7; ERK8
• NCBI Protein Information: mitogen-activated protein kinase 15; ERK-7; ERK-8; MAPK 15; MAP kinase 15; extracellular regulated kinase 8 delta; extracellular signal regulated kinase 8; extracellular signal-regulated kinase 7; extracellular signal-regulated kinase 8
• UniProt Protein Name: Mitogen-activated protein kinase 15
• UniProt Gene Name: MAPK15
• UniProt Synonym Gene Names: ERK7; ERK8; MAP kinase 15; MAPK 15; ERK-7; ERK-8
• UniProt Entry Name: MK15_HUMAN

Uniprot Description

ERK7: In vitro, phosphorylates MBP. Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Kinase, protein; EC 2.7.11.24; Protein kinase, Ser/Thr (non-receptor); Protein kinase, CMGC; CMGC group; MAPK family; Erk7 subfamily

Chromosomal Location of Human Ortholog: -

Cellular Component: extracellular region; intracellular; nucleus

Molecular Function: MAP kinase activity; SH3 domain binding; ATP binding

Biological Process: negative regulation of DNA replication; positive regulation of protein ubiquitination; protein amino acid autophosphorylation; positive regulation of protein catabolic process; MAPKKK cascade; negative regulation of transcription from RNA polymerase II promoter; positive regulation of protein amino acid phosphorylation; response to estradiol stimulus