Western Blot (WB)
(PHLDA1 Antibody (N-term) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the PHLDA1 antibody detected the PHLDA1 protein (arrow).)
Rabbit anti-Human PHLDA1 Polyclonal Antibody | anti-PHLDA1 antibody
PHLDA1 Antibody (N-term)
Gene Names
PHLDA1; PHRIP; TDAG51; DT1P1B11
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
PHLDA1; Polyclonal Antibody; PHLDA1 Antibody (N-term); Pleckstrin homology-like domain family A member 1; Apoptosis-associated nuclear protein; Proline- and glutamine-rich protein; PQ-rich protein; PQR protein; Proline- and histidine-rich protein; T-cell death-associated gene 51 protein; PHRIP; TDAG51; anti-PHLDA1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This PHLDA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-49 amino acids from the N-terminal region of human PHLDA1.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.3 (varies by lot)
Sequence Positions
23-49
Sequence Length
401
Applicable Applications for anti-PHLDA1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(PHLDA1 Antibody (N-term) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the PHLDA1 antibody detected the PHLDA1 protein (arrow).)
Western Blot (WB)
(PHLDA1 Antibody (N-term) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the PHLDA1 antibody detected the PHLDA1 protein (arrow).)
Related Product Information for anti-PHLDA1 antibody
This gene encodes an evolutionarily conserved
proline-histidine rich nuclear protein. The encoded protein may
play an important role in the anti-apoptotic effects of
insulin-like growth factor-1.
proline-histidine rich nuclear protein. The encoded protein may
play an important role in the anti-apoptotic effects of
insulin-like growth factor-1.
Product Categories/Family for anti-PHLDA1 antibody
References
Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)
Marchiori, A.C., et al. Braz. J. Med. Biol. Res. 41(7):579-582(2008)
Nagai, M.A., et al. Breast Cancer Res. Treat. 106(1):49-56(2007)
Xi, Z.Q., et al. Neurosci. Lett. 425(1):53-58(2007)
Meier-Noorden, M., et al. Gene 338(2):197-207(2004)
Marchiori, A.C., et al. Braz. J. Med. Biol. Res. 41(7):579-582(2008)
Nagai, M.A., et al. Breast Cancer Res. Treat. 106(1):49-56(2007)
Xi, Z.Q., et al. Neurosci. Lett. 425(1):53-58(2007)
Meier-Noorden, M., et al. Gene 338(2):197-207(2004)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
45016
NCBI Official Full Name
pleckstrin homology-like domain family A member 1
NCBI Official Synonym Full Names
pleckstrin homology-like domain, family A, member 1
NCBI Official Symbol
PHLDA1
NCBI Official Synonym Symbols
PHRIP; TDAG51; DT1P1B11
NCBI Protein Information
pleckstrin homology-like domain family A member 1
UniProt Protein Name
Pleckstrin homology-like domain family A member 1
Protein Family
UniProt Gene Name
PHLDA1
UniProt Synonym Gene Names
PHRIP; TDAG51; PQ-rich protein; PQR protein
UniProt Entry Name
PHLA1_HUMAN
NCBI Description
This gene encodes an evolutionarily conserved proline-histidine rich nuclear protein. The encoded protein may play an important role in the anti-apoptotic effects of insulin-like growth factor-1. [provided by RefSeq, Jul 2008]
Uniprot Description
PHLDA1: Seems to be involved in regulation of apoptosis. May be involved in detachment-mediated programmed cell death. May mediate apoptosis during neuronal development. May be involved in regulation of anti-apoptotic effects of IGF1. May be involved in translational regulation.
Protein type: Nucleolus; Apoptosis
Chromosomal Location of Human Ortholog: 12q15
Cellular Component: nucleoplasm; cytoplasmic vesicle membrane; plasma membrane; nucleolus
Molecular Function: protein binding
Biological Process: positive regulation of apoptosis; apoptosis; forebrain neuron differentiation; FasL biosynthetic process
Research Articles on PHLDA1
1. PHLDA1 expression is a useful addition in differentiating trichoblastoma and basal cell carcinoma.
Similar Products
Product Notes
The PHLDA1 phlda1 (Catalog #AAA9211256) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 23-49. The PHLDA1 Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PHLDA1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the PHLDA1 phlda1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PHLDA1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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