Rabbit anti-Mouse Period Clock Protein 1 Polyclonal Antibody | anti-per antibody

Period Clock Protein 1 (PER1, RIGUI)

Cat. Num. AAA615848

• Gene Names: per; CG2647; Clk; clk-6; DmelCG2647; dmper; dper; dPER; EG:155E2.4; mel_per; Per; PER
• Reactivity: Mouse
• Applications: ELISA, Western Blot, Immunohistochemistry, Immunofluorescence
• Purity: Affinity Purified; Purified by immunoaffinity chromatography.
• Synonyms: Period Clock Protein 1; Polyclonal Antibody; Period Clock Protein 1 (PER1; RIGUI); Anti -Period Clock Protein 1 (PER1; anti-per antibody

• Host: Rabbit
• Reactivity: Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes mouse Period Clock Protein 1. No significant homology is seen with Per2, Per3, dPER or other known proteins. Species Sequence Homology: human and rat, 93%
• Purity/Purification: Affinity Purified; Purified by immunoaffinity chromatography.
• Form/Format: Supplied as a lyophilized powder from PBS, 0.1% BSA. Reconstitute with 100ul sterile PBS.

• Applicable Applications for anti-per antibody: ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
• Application Notes: Suitable for use in ELISA, Western Blot, Immunohistochemistry and Immunofluorescence.; Dilution: ELISA: 1:10,000-1:100,000 using 50-100ng of control peptide/well.; Western Blot: 1-10ug/ml using ECL.; Immunohistochemistry: 2-20ug/ml; Immunofluorescence: 2-20ug/ml
• Immunogen: Synthetic peptide corresponding to a 16aa sequence from mouse Period Clock Protein 1 conjugated to KLH. Epitope: ~C-terminal mapping downstream of the SG repeat of mouse Period Clock Protein 1.
• Preparation and Storage: Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Related Product Information for anti-per antibody

Several endogenous factors have been linked to rhythmicity or circadian behavior of living organisms. In Drosophila, the genes period (dPer) and timeless (tim), and in Neurospora frequency (frq), have been proposed to be responsible for their circadian rhythm. Recently human and mouse genes encoding a basic helix-loop-helix (bHLH) and Per-ARNT-Sim (PAS)-domain with significant similarity to the Drosophila Period have been reported. The cDNA sequences of hPER and mPer1 (also named RIGUI) are predicted to encode for proteins of length 1290 and 1291 amino acids respectively. Homologues of mPer1 designated Per 2 (1257aa) and Per3 (1113aa) have also been cloned. Both Per1 and Per2 levels show circadian rhythm in the SCN and eyes. It has been suggested that mPer regulates neuronal activity in the SCN. Using genetic approach, a single mutation (A to T in the Clock gene affects circadian rhythmicity in mice.

Product Categories/Family for anti-per antibody

Antibodies; Abs to Circadian Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 442614977
• NCBI GeneID: 31251
• NCBI Accession #: NP_001259194.1
• NCBI GenBank Nucleotide #: NM_001272265.1
• NCBI Official Full Name: period, isoform B
• NCBI Official Synonym Full Names: period
• NCBI Official Symbol: per
• NCBI Official Synonym Symbols: CG2647; Clk; clk-6; DmelCG2647; dmper; dper; dPER; EG:155E2.4; mel_per; Per; PER
• NCBI Protein Information: CG2647 gene product from transcript CG2647-RA; CG2647-PA; CG2647-PB; PERIOD; clock; clock-6; dperiod; per-PA; per-PB; period clock protein
• Protein Family: Period circadian protein