Western Blot (WB)
(Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane: Human normal lung tissue, Primary antibody: 862383(PTX3 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds)
Rabbit anti-Human, Mouse Pentraxin 3/PTX3 Polyclonal Antibody | anti-3/PTX3 antibody
Pentraxin 3/PTX3 Rabbit pAb
Gene Names
PTX3; TSG-14; TNFAIP5
Reactivity
Human, Mouse
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Affinity purified
Synonyms
Pentraxin 3/PTX3; Polyclonal Antibody; Pentraxin 3/PTX3 Rabbit pAb; pentraxin 3; long; TSG-14; TNFAIP5; anti-3/PTX3 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
Rabbit IgG
Purity/Purification
Affinity purified
Form/Format
pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Applicable Applications for anti-3/PTX3 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P)
Application Notes
WB: 1:200-1:1000
ELISA: 1:1000-1:2000
IHC: 1:25-1:100
ELISA: 1:1000-1:2000
IHC: 1:25-1:100
Immunogen
Synthetic peptide of human PTX3
Conjugation
Unconjugated
Molecular Function
Plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility.
Modification
Unmodified
Cell Position
Secreted
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Western Blot (WB)
(Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane: Human normal lung tissue, Primary antibody: 862383(PTX3 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds)
Western Blot (WB)
(Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane: Human normal lung tissue, Primary antibody: 862383(PTX3 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds)
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using 862383(PTX3 Antibody) at dilution 1/40.(Original magnification: ×200))
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using 862383(PTX3 Antibody) at dilution 1/40.(Original magnification: ×200))
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 862383(PTX3 Antibody) at dilution 1/40. (Original magnification: ×200))
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 862383(PTX3 Antibody) at dilution 1/40. (Original magnification: ×200))
Related Product Information for anti-3/PTX3 antibody
Ptx3, also known as tumor necrosis factor-stimulated gene sequence-14 (TSG14), is a secreted pattern-recognition receptor that has a non-redundant role in resistance to selected microbial agents. Ptx3 belongs to the family of “long pentraxins”, which have C-terminal pentraxin domains and novel amino-terminal domains. Ptx3 binds selected pathogens, including Aspergillus fumigatus, Pseudomonas aeruginosa and Salmonella typhimurium. It is synthesized in IgA glomerulonephritis and activates mesangial cells.
Product Categories/Family for anti-3/PTX3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
41,976 Da
NCBI Official Full Name
pentraxin-related protein PTX3
NCBI Official Synonym Full Names
pentraxin 3, long
NCBI Official Symbol
PTX3
NCBI Official Synonym Symbols
TSG-14; TNFAIP5
NCBI Protein Information
pentraxin-related protein PTX3; pentraxin-3; TNF alpha-induced protein 5; pentaxin-related protein PTX3; tumor necrosis factor alpha-induced protein 5; tumor necrosis factor, alpha-induced protein 5; tumor necrosis factor-inducible protein TSG-14; tumor n
UniProt Protein Name
Pentraxin-related protein PTX3
UniProt Gene Name
PTX3
UniProt Synonym Gene Names
TNFAIP5; TSG14; TNF alpha-induced protein 5; TSG-14
UniProt Entry Name
PTX3_HUMAN
Uniprot Description
PTX3: Plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self- components and female fertility.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 3q25
Cellular Component: extracellular space; extracellular region
Molecular Function: complement component C1q binding; zymosan binding; virion binding
Biological Process: positive regulation of nitric oxide biosynthetic process; negative regulation of virion penetration into host cell; positive regulation of phagocytosis; innate immune response; response to yeast; opsonization; inflammatory response
Research Articles on 3/PTX3
Similar Products
Product Notes
The 3/PTX3 ptx3 (Catalog #AAA4758563) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Pentraxin 3/PTX3 Rabbit pAb reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Pentraxin 3/PTX3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P). WB: 1:200-1:1000 ELISA: 1:1000-1:2000 IHC: 1:25-1:100. Researchers should empirically determine the suitability of the 3/PTX3 ptx3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Pentraxin 3/PTX3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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