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Immunohistochemistry (IHC) (Anti-PEAK1 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Rabbit anti-Mouse, Human PEAK1 / SGK269 Polyclonal Antibody | anti-PEAK1 / SGK269 antibody

Anti-PEAK1 / SGK269 Antibody (aa672-699) IHC-plus

Gene Names
PEAK1; SGK269
Reactivity
Mouse, Human
Applications
Immunohistochemistry, Western Blot
Purity
Immunoaffinity purified
Synonyms
PEAK1 / SGK269; Polyclonal Antibody; Anti-PEAK1 / SGK269 Antibody (aa672-699) IHC-plus; Rabbit Polyclonal to Human PEAK1 / SGK269; Human PEAK1 / SGK269; sugen kinase 269; tyrosine-protein kinase SgK269; anti-PEAK1 / SGK269 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mouse, Human
Clonality
Polyclonal
Specificity
Human Sgk269
Purity/Purification
Immunoaffinity purified
Form/Format
PBS, 0.09% sodium azide
Sequence Length
1746
Applicable Applications for anti-PEAK1 / SGK269 antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes
IHC-P (5 ug/ml)
WB (1:1000)
Immunogen
PEAK1 / SGK269 antibody was raised against kLH-conjugated synthetic peptide from N-terminal region of human SGK269.
Immunogen Description
KLH-conjugated synthetic peptide from N-terminal region of human SGK269.
Immunogen Type
Synthetic peptide
Antigen Modification
aa672-699
Target Species
Human
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months.
For long term storage store at -20 degree C.

Immunohistochemistry (IHC)

(Anti-PEAK1 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-PEAK1 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Western Blot (WB)

(SGK269 Antibody western blot of mouse liver tissue lysates (35 ug/lane). The SGK269 antibody detected the SGK269 protein (arrow).)

Western Blot (WB) (SGK269 Antibody western blot of mouse liver tissue lysates (35 ug/lane). The SGK269 antibody detected the SGK269 protein (arrow).)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
193,106 Da
NCBI Official Full Name
pseudopodium-enriched atypical kinase 1
NCBI Official Synonym Full Names
pseudopodium enriched atypical kinase 1
NCBI Official Symbol
PEAK1
NCBI Official Synonym Symbols
SGK269
NCBI Protein Information
pseudopodium-enriched atypical kinase 1
UniProt Protein Name
Pseudopodium-enriched atypical kinase 1
UniProt Gene Name
PEAK1
UniProt Synonym Gene Names
KIAA2002
UniProt Entry Name
PEAK1_HUMAN

NCBI Description

This gene encodes a non-receptor tyrosine kinase that is a member of the new kinase family three (NFK3) family. In migrating cells, the encoded protein is associated with the actin cytoskeleton and focal adhesions and promotes developing focal adhesion elongation. This protein may play a role in the regulation of cell migration, proliferation and cancer metastasis. [provided by RefSeq, Mar 2014]

Uniprot Description

PEAK1: Tyrosine kinase that may play a role in cell spreading and migration on fibronectin. May directly or indirectly affect phosphorylation levels of cytoskeleton-associated proteins MAPK1/ERK and PXN. Belongs to the protein kinase superfamily.

Protein type: Protein kinase, Ser/Thr (non-receptor); Kinase, protein; Protein kinase, Other; EC 2.7.10.2; Other group; NKF3 family

Chromosomal Location of Human Ortholog: 15q24.3

Cellular Component: actin cytoskeleton; cytoplasm; focal adhesion; nucleoplasm; plasma membrane

Molecular Function: ATP binding; non-membrane spanning protein tyrosine kinase activity; protein binding

Biological Process: cell migration; peptidyl-tyrosine phosphorylation; protein amino acid autophosphorylation

Research Articles on PEAK1 / SGK269

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Product Notes

The PEAK1 / SGK269 peak1 (Catalog #AAA2400009) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-PEAK1 / SGK269 Antibody (aa672-699) IHC-plus reacts with Mouse, Human and may cross-react with other species as described in the data sheet. AAA Biotech's PEAK1 / SGK269 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Western Blot (WB). IHC-P (5 ug/ml) WB (1:1000). Researchers should empirically determine the suitability of the PEAK1 / SGK269 peak1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PEAK1 / SGK269, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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