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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human kidney tissue slide using MBS7604042 (SLC5A2 Antibody) at dilution of 1:200)

Rabbit anti-Human SGLT2 Polyclonal Antibody | anti-SGLT2 antibody

SGLT2 Rabbit Polyclonal

Gene Names
SLC5A2; SGLT2
Reactivity
Human
Applications
ELISA, Immunohistochemistry, Western Blot
Purity
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Synonyms
SGLT2; Polyclonal Antibody; SGLT2 Rabbit Polyclonal; anti-SGLT2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Form/Format
Liquid
Sequence Length
672
Applicable Applications for anti-SGLT2 antibody
ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
Immunogen
Solute carrier family 5 (sodium/glucose cotransporter), member 2
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human kidney tissue slide using MBS7604042 (SLC5A2 Antibody) at dilution of 1:200)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human kidney tissue slide using MBS7604042 (SLC5A2 Antibody) at dilution of 1:200)

Western Blot (WB)

(A549 cells were subjected to SDS PAGE followed by western blot with MBS7604042 (SLC5A2 Antibody) at dilution of 1:600)

Western Blot (WB) (A549 cells were subjected to SDS PAGE followed by western blot with MBS7604042 (SLC5A2 Antibody) at dilution of 1:600)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
49,357 Da
NCBI Official Full Name
sodium/glucose cotransporter 2
NCBI Official Synonym Full Names
solute carrier family 5 member 2
NCBI Official Symbol
SLC5A2
NCBI Official Synonym Symbols
SGLT2
NCBI Protein Information
sodium/glucose cotransporter 2
UniProt Protein Name
Sodium/glucose cotransporter 2
UniProt Gene Name
SLC5A2
UniProt Synonym Gene Names
SGLT2; Na(+)/glucose cotransporter 2
UniProt Entry Name
SC5A2_HUMAN

NCBI Description

This gene encodes a member of the sodium glucose cotransporter family which are sodium-dependent glucose transport proteins. The encoded protein is the major cotransporter involved in glucose reabsorption in the kidney. Mutations in this gene are associated with renal glucosuria. Two transcript variants, one protein-coding and one not, have been found for this gene. [provided by RefSeq, Feb 2015]

Uniprot Description

SLC5A2: Sodium-dependent glucose transporter. Has a Na(+) to glucose coupling ratio of 1:1. Defects in SLC5A2 are the cause of renal glucosuria (GLYS1). GLYS1 is an autosomal recessive disorder characterized by a normal fasting serum glucose concentration and persistent isolated glucosuria, with a normal glucose tolerance test. Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.

Protein type: Membrane protein, integral; Transporter; Membrane protein, multi-pass; Transporter, SLC family

Chromosomal Location of Human Ortholog: 16p11.2

Cellular Component: brush border membrane; integral to membrane; integral to plasma membrane; plasma membrane

Molecular Function: glucose:sodium symporter activity; low-affinity glucose:sodium symporter activity

Biological Process: carbohydrate metabolic process; sodium ion transport; transport

Disease: Renal Glucosuria

Research Articles on SGLT2

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Product Notes

The SGLT2 slc5a2 (Catalog #AAA7604042) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SGLT2 Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SGLT2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB). Researchers should empirically determine the suitability of the SGLT2 slc5a2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SGLT2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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