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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human colon cancer using MBS7050317 at dilution of 1:100)

Rabbit anti-Human PDS5A Polyclonal Antibody | anti-PDS5A antibody

PDS5A Antibody

Gene Names
PDS5A; PIG54; SCC112; SCC-112
Reactivity
Human
Applications
ELISA, Immunohistochemistry, Immunofluorescence
Purity
>95%, Protein G purified
Synonyms
PDS5A; Polyclonal Antibody; PDS5A Antibody; Sister chromatid cohesion protein PDS5 homolog A; Cell proliferation-inducing gene 54 protein; Sister chromatid cohesion protein 112; SCC-112; anti-PDS5A antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Sequence Length
1337
Applicable Applications for anti-PDS5A antibody
ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes
IHC: 1: 20-1: 200
IF: 1: 50-1: 200
Immunogen
Recombinant Human Sister chromatid cohesion protein PDS5 homolog A protein (2-134AA)
Preservative
0.03% Proclin 300
Constituents
50% Glycerol, 0.01M PBS, PH 7.4
Conjugation
Non-conjugated
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-50780 / sc-50782
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human colon cancer using MBS7050317 at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human colon cancer using MBS7050317 at dilution of 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human ovarian cancer using MBS7050317 at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human ovarian cancer using MBS7050317 at dilution of 1:100)

Immunohistochemistry (IHC)

(Immunofluorescent analysis of Hela cells using MBS7050317 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

Immunohistochemistry (IHC) (Immunofluorescent analysis of Hela cells using MBS7050317 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
Related Product Information for anti-PDS5A antibody
Probable regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. May couple sister chromatid cohesion during mitosis to DNA replication. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
69,000 Da
NCBI Official Full Name
sister chromatid cohesion protein PDS5 homolog A isoform 1
NCBI Official Synonym Full Names
PDS5 cohesin associated factor A
NCBI Official Symbol
PDS5A
NCBI Official Synonym Symbols
PIG54; SCC112; SCC-112
NCBI Protein Information
sister chromatid cohesion protein PDS5 homolog A
UniProt Protein Name
Sister chromatid cohesion protein PDS5 homolog A
UniProt Gene Name
PDS5A
UniProt Synonym Gene Names
SCC-112
UniProt Entry Name
PDS5A_HUMAN

NCBI Description

The protein encoded by this gene binds to the cohesin complex and associates with chromatin through most of the cell cycle. The encoded protein may play a role in regulating sister chromatid cohesion during mitosis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010]

Uniprot Description

SCC-112: a cell-cycle regulated protein.

Protein type: Cell cycle regulation

Chromosomal Location of Human Ortholog: 4p14

Cellular Component: chromatin; chromosome; chromosome, pericentric region; cytosol; nucleoplasm; nucleus; plasma membrane

Molecular Function: protein binding

Biological Process: DNA repair; mitotic sister chromatid cohesion; negative regulation of DNA replication; sister chromatid cohesion

Research Articles on PDS5A

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Product Notes

The PDS5A pds5a (Catalog #AAA7050317) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PDS5A Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PDS5A can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF). IHC: 1: 20-1: 200 IF: 1: 50-1: 200. Researchers should empirically determine the suitability of the PDS5A pds5a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PDS5A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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