Rabbit anti-Human, Rat PDP1 Polyclonal Antibody | anti-PPAPDC2 antibody
PDP1 (Pyruvate Dehyrogenase Phosphatase Catalytic Subunit 1, PDH, PDP, PDP 1, PDPC, PDPC 1, PPM2C, Protein phosphatase 2C)
Purified by ammonium sulfate precipitation.
Purified by ammonium sulfate precipitation.
Dilution: Western Blot: 1:500
Immunohistochemistry (IHC)
(PP2C staining in normal human testis, tissue pretreated with citrate buffer, pH 6.0. MBS6004030 was diluted to 1:100, using IHC-Select® detection with HRP-DAB.)
Western Blot (WB)
(Western Blot Analysis: L6 lysate was resolved by electrophoresis, transferred to PVDF membrane and probed with MBS6004030 (1:500 dilution of this lot). Proteins were visualized using a donkey anti-rabbit secondary antibody conjugated to HRP and a chemiluminescence detection system. Arrow indicates protein PP2C ALPHA/BETA (~46kD).)
Testing Data
(Huvec lysate (Lane 1) and L6 lysate (Lane 2) were resolved by electrophoresis, transferred to PVDF membrane and probed with MBS6004030 (1:500 dilution of a previous lot). Proteins were visualized using a donkey anti-rabbit secondary antibody conjugated to HRP and a chemiluminescence detection system. Arrow indicates protein PP2C ALPHA/BETA (~46kD).)
NCBI and Uniprot Product Information
Uniprot Description
PPAPDC2: Phosphatase that dephosphorylates presqualene diphosphate (PSDP) into presqualene monophosphate (PSMP), suggesting that it may be indirectly involved in innate immunity. PSDP is a bioactive lipid that rapidly remodels to presqualene monophosphate PSMP upon cell activation. Displays diphosphate phosphatase activity with a substrate preference for PSDP > FDP > phosphatidic acid. Belongs to the PA-phosphatase related phosphoesterase family.
Protein type: Membrane protein, integral; Phosphatase; Membrane protein, multi-pass; EC 3.1.3.-
Chromosomal Location of Human Ortholog: 9p24.1
Cellular Component: integral to membrane
Molecular Function: hydrolase activity
Biological Process: metabolic process
Research Articles on PPAPDC2
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Product Notes
The PPAPDC2 ppapdc2 (Catalog #AAA6004030) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PDP1 (Pyruvate Dehyrogenase Phosphatase Catalytic Subunit 1, PDH, PDP, PDP 1, PDPC, PDPC 1, PPM2C, Protein phosphatase 2C) reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PDP1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Dilution: Western Blot: 1:500. Researchers should empirically determine the suitability of the PPAPDC2 ppapdc2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PDP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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