Western Blot (WB)
(Western blot analysis of PDE2A expression in Human fetal brain lysate.)
Rabbit PDE2A Polyclonal Antibody | anti-PDE2A antibody
PDE2A Rabbit pAb
Western Blot (WB)
(Western blot analysis of PDE2A expression in Human fetal brain lysate.)
Western Blot (WB)
(Western blot analysis of PDE2A expression in Human fetal brain lysate.)
NCBI and Uniprot Product Information
Uniprot Description
PDE2A: Cyclic nucleotide phosphodiesterase with a dual- specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Belongs to the cyclic nucleotide phosphodiesterase family. PDE2 subfamily. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Mitochondrial; Phosphodiesterase; EC 3.1.4.17; Nucleotide Metabolism - purine
Chromosomal Location of Human Ortholog: 11q13.4
Cellular Component: presynaptic membrane; Golgi apparatus; mitochondrial matrix; axon; endoplasmic reticulum; perinuclear region of cytoplasm; dendrite; cytoplasm; plasma membrane; nucleus; cytosol
Molecular Function: protein binding; protein homodimerization activity; TPR domain binding; calcium channel activity; metal ion binding; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity; cGMP binding; cyclic-nucleotide phosphodiesterase activity; drug binding; cAMP binding
Biological Process: monocyte differentiation; metabolic process; cGMP-mediated signaling; cAMP catabolic process; negative regulation of transcription from RNA polymerase II promoter; positive regulation of vascular permeability; cAMP-mediated signaling; negative regulation of cAMP biosynthetic process; negative regulation of protein import into nucleus, translocation; negative regulation of vascular permeability; regulation of cGMP metabolic process; cGMP catabolic process; blood coagulation; protein targeting to mitochondrion; positive regulation of inflammatory response
Research Articles on PDE2A
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Product Notes
The PDE2A pde2a (Catalog #AAA4757608) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PDE2A Rabbit pAb reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PDE2A can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the PDE2A pde2a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PDE2A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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