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Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Human tonsil tissue using at dilution 1/20,)

Rabbit anti-Human PCDHA6 Polyclonal Antibody | anti-PCDHA6 antibody

PCDHA6 Antibody

Gene Names
PCDHA6; CNR2; CNRN2; CNRS2; CRNR2; PCDH-ALPHA6
Reactivity
Human
Applications
Immunohistochemistry
Purity
Antigen Affinity Purification
Synonyms
PCDHA6; Polyclonal Antibody; PCDHA6 Antibody; CNR2; CNRN2; CNRS2; CRNR2; PCDH-ALPHA6; anti-PCDHA6 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total PCDHA6 protein.
Purity/Purification
Antigen Affinity Purification
Form/Format
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Concentration
0.8 mg/ml (varies by lot)
Sequence Length
950
Applicable Applications for anti-PCDHA6 antibody
Immunohistochemistry (IHC)
Application Notes
Immunohistochemistry: 1:30-1:150
Immunogen
Synthetic peptide of human PCDHA6
Immunogen Type
Peptide
Preparation and Storage
Store at -20 degree C

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Human tonsil tissue using at dilution 1/20,)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Human tonsil tissue using at dilution 1/20,)
Related Product Information for anti-PCDHA6 antibody
This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
Product Categories/Family for anti-PCDHA6 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
86,845 Da
NCBI Official Full Name
protocadherin alpha-6 isoform 1
NCBI Official Synonym Full Names
protocadherin alpha 6
NCBI Official Symbol
PCDHA6
NCBI Official Synonym Symbols
CNR2; CNRN2; CNRS2; CRNR2; PCDH-ALPHA6
NCBI Protein Information
protocadherin alpha-6
UniProt Protein Name
Protocadherin alpha-6
Protein Family
UniProt Gene Name
PCDHA6
UniProt Synonym Gene Names
CNRS2; PCDH-alpha-6
UniProt Entry Name
PCDA6_HUMAN

Uniprot Description

PCDHA6: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 5q31

Cellular Component: integral to plasma membrane

Biological Process: cell adhesion; cell-cell signaling; nervous system development

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Product Notes

The PCDHA6 pcdha6 (Catalog #AAA9415335) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PCDHA6 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PCDHA6 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). Immunohistochemistry: 1:30-1:150. Researchers should empirically determine the suitability of the PCDHA6 pcdha6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PCDHA6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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