Western Blot (WB)
(WB Suggested Anti-PARG AntibodyTitration: 1.0 ug/mlPositive Control: Jurkat Whole Cell)
Rabbit PARG Polyclonal Antibody | anti-PARG antibody
PARG antibody - C-terminal region
Western Blot (WB)
(WB Suggested Anti-PARG AntibodyTitration: 1.0 ug/mlPositive Control: Jurkat Whole Cell)
Western Blot (WB)
(WB Suggested Anti-PARG AntibodyTitration: 1.0 ug/mlPositive Control: Jurkat Whole Cell)
Target Description: Poly(ADP-ribose) glycohydrolase (PARG) is the major enzyme responsible for the catabolism of poly(ADP-ribose), a reversible covalent-modifier of chromosomal proteins. The protein is found in many tissues and may be subject to proteolysis generating smaller, active products.
NCBI and Uniprot Product Information
NCBI Description
Poly(ADP-ribose) glycohydrolase (PARG) is the major enzyme responsible for the catabolism of poly(ADP-ribose), a reversible covalent-modifier of chromosomal proteins. The protein is found in many tissues and may be subject to proteolysis generating smaller, active products. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2015]
Uniprot Description
PARG: Poly(ADP-ribose) synthesized after DNA damage is only present transiently and is rapidly degraded by poly(ADP-ribose) glycohydrolase. Poly(ADP-ribose) metabolism may be required for maintenance of the normal function of neuronal cells. Belongs to the poly(ADP-ribose) glycohydrolase family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.2.1.143; Hydrolase
Chromosomal Location of Human Ortholog: 10q11.23
Cellular Component: cytoplasm; cytosol; intracellular membrane-bound organelle; mitochondrial matrix; nucleoplasm; nucleus
Molecular Function: poly(ADP-ribose) glycohydrolase activity; protein binding
Biological Process: ATP generation from poly-ADP-D-ribose; carbohydrate metabolic process
Research Articles on PARG
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Product Notes
The PARG parg (Catalog #AAA3216080) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PARG antibody - C-terminal region reacts with Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PARG can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the PARG parg for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: LFTEVLDHNE CLIITGTEQY SEYTGYAETY RWSRSHEDGS ERDDWQRRCT. It is sometimes possible for the material contained within the vial of "PARG, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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