Immunohistochemistry (IHC)
(Human testis: Formalin-Fixed Paraffin-Embedded (FFPE).)
Rabbit anti-Human, Mouse PARC Polyclonal Antibody | anti-PARC antibody
PARC (p53-associated Parkin-like Cytoplasmic Protein, DKFZp686G1042, DKFZp686P2024, H7AP1, KIAA0708, OTTHUMP00000039816, RP3 330M21.2, UbcH7-associated Protein 1)
Reactivity
Human, Mouse
Applications
Western Blot, Immunohistochemistry
Purity
Affinity PurifiedPurified by immunoaffinity chromatography.
Synonyms
PARC; Polyclonal Antibody; PARC (p53-associated Parkin-like Cytoplasmic Protein; DKFZp686G1042; DKFZp686P2024; H7AP1; KIAA0708; OTTHUMP00000039816; RP3 330M21.2; UbcH7-associated Protein 1); Anti -PARC (p53-associated Parkin-like Cytoplasmic Protein; anti-PARC antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human PARC. Species Crossreactivity: Mouse.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a liquid.
Applicable Applications for anti-PARC antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Suitable for use in Immunohistochemistry and Western Blot.
Dilution: Immunohistochemistry: 5ug/ml (Paraffin Embedded Only).
Western Blot: 1-2ug/ml
Dilution: Immunohistochemistry: 5ug/ml (Paraffin Embedded Only).
Western Blot: 1-2ug/ml
Immunogen
Synthetic peptide corresponding to 17aa near the carboxy terminus of human PARC.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Immunohistochemistry (IHC)
(Human testis: Formalin-Fixed Paraffin-Embedded (FFPE).)
Immunohistochemistry (IHC)
(Human testis: Formalin-Fixed Paraffin-Embedded (FFPE).)
Related Product Information for anti-PARC antibody
PARC (p53 associated parkin like cytoplasmic protein) antibody directly interacted and formed an approximately 1MD complex with p53 in the cytoplasm of unstressed cells. In the absence of stress, inactivation of PARC induced nuclear localization of endogenous p53 and activated p53 dependent apoptosis. Overexpression of PARC promoted cytoplasmic sequestration of ectopic p53. Furthermore, abnormal cytoplasmic localization of p53 was observed in a number of neuroblastoma cell lines; RNA interference-mediated reduction of endogenous PARC significantly sensitized these neuroblastoma cells in the DNA damage response. These results revealed that PARC is a critical regulator in controlling p53 subcellular localization and subsequent function.
Product Categories/Family for anti-PARC antibody
NCBI and Uniprot Product Information
Uniprot Description
Function: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
Catalytic activity: RX + glutathione = HX + R-S-glutathione.
Tissue specificity: Abundant in seedlings and roots. It is also found in the shoot tips, flowers and leaves.
Induction: By auxin.
Sequence similarities: Belongs to the GST superfamily. Phi family.Contains 1 GST C-terminal domain.Contains 1 GST N-terminal domain.
Similar Products
Product Notes
The PARC parc (Catalog #AAA628580) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PARC (p53-associated Parkin-like Cytoplasmic Protein, DKFZp686G1042, DKFZp686P2024, H7AP1, KIAA0708, OTTHUMP00000039816, RP3 330M21.2, UbcH7-associated Protein 1) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's PARC can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Suitable for use in Immunohistochemistry and Western Blot. Dilution: Immunohistochemistry: 5ug/ml (Paraffin Embedded Only). Western Blot: 1-2ug/ml. Researchers should empirically determine the suitability of the PARC parc for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PARC, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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