Western Blot (WB)
(mouse liver tissue were subjected to SDS PAGE followed by western blot with MBS7602372 (PAPD5 antibody) at dilution of 1:1000)
Rabbit PAPD5 Polyclonal Antibody | anti-PAPD5 antibody
PAPD5 Rabbit Polyclonal
Gene Names
PAPD5; TRF4-2
Reactivity
Human, Mouse, Rat; other species are not tested.
Applications
ELISA, Western Blot, Immunoprecipitation
Purity
>=95% as determined by SDS-PAGEImmunogen Affinity Purified
Synonyms
PAPD5; Polyclonal Antibody; PAPD5 Rabbit Polyclonal; Terminal uridylyltransferase 3; TRF4 2; TUTase 3; anti-PAPD5 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat; other species are not tested.
Clonality
Polyclonal
Isotype
IgG
Specificity
Please decide the specificity by homology.
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Immunogen Affinity Purified
Form/Format
Liquid
Sequence Length
693
Applicable Applications for anti-PAPD5 antibody
ELISA, WB, IP
Application Notes
WB: 1:500 - 1:2000
Immunogen
PAP associated domain containing 5
Calculated MW
50 kDa, 80kDa
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.3
Preparation and Storage
Store at -20°C for 24 months (Avoid repeated freeze / thaw cycles.)
Western Blot (WB)
(mouse liver tissue were subjected to SDS PAGE followed by western blot with MBS7602372 (PAPD5 antibody) at dilution of 1:1000)
Western Blot (WB)
(mouse liver tissue were subjected to SDS PAGE followed by western blot with MBS7602372 (PAPD5 antibody) at dilution of 1:1000)
Related Product Information for anti-PAPD5 antibody
Catalytic subunit of a TRAMP-like complex which has a poly(A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism. Polyadenylation with short oligo(A) tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates. Doesn't need a cofactor for polyadenylation activity(in vitro). Plays a role in replication-dependent histone mRNA degradation, probably through terminal uridylation of mature histone mRNAs. May play a role in sister chromatid cohesion.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
non-canonical poly(A) RNA polymerase PAPD5 isoform X4
NCBI Official Synonym Full Names
PAP associated domain containing 5
NCBI Official Symbol
PAPD5
NCBI Official Synonym Symbols
TRF4-2
NCBI Protein Information
non-canonical poly(A) RNA polymerase PAPD5
UniProt Protein Name
Non-canonical poly(A) RNA polymerase PAPD5
Protein Family
UniProt Gene Name
PAPD5
UniProt Synonym Gene Names
TUTase 3; TRF4-2
UniProt Entry Name
PAPD5_HUMAN
Uniprot Description
PAPD5: Plays a role in replication-dependent histone mRNA degradation. May be involved in the terminal uridylation of mature histone mRNAs before their degradation is initiated. DNA polymerase, probably involved in DNA repair. May play a role in sister chromatid cohesion. Belongs to the DNA polymerase type-B-like family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Transferase; Nucleolus; EC 2.7.7.19
Chromosomal Location of Human Ortholog: 16q12.1
Cellular Component: cytoplasm; nucleolus
Molecular Function: DNA binding; DNA-directed DNA polymerase activity; metal ion binding; polynucleotide adenylyltransferase activity
Biological Process: cell division; mitosis; mRNA processing; rRNA processing
Research Articles on PAPD5
Similar Products
Product Notes
The PAPD5 papd5 (Catalog #AAA7602372) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PAPD5 Rabbit Polyclonal reacts with Human, Mouse, Rat; other species are not tested. and may cross-react with other species as described in the data sheet. AAA Biotech's PAPD5 can be used in a range of immunoassay formats including, but not limited to, ELISA, WB, IP. WB: 1:500 - 1:2000. Researchers should empirically determine the suitability of the PAPD5 papd5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PAPD5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
