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Western Blot (WB) (PAOX Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the PAOX antibody detected the PAOX protein (arrow).)

Rabbit anti-Human, mouse PAOX Polyclonal Antibody | anti-PAOX antibody

PAOX Antibody (Center)

Gene Names
PAOX; PAO
Reactivity
Human, mouse
Applications
Western Blot, ELISA, Immunohistochemistry
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
PAOX; Polyclonal Antibody; PAOX Antibody (Center); Peroxisomal N(1)-acetyl-spermine/spermidine oxidase; Polyamine oxidase; PAO; anti-PAOX antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, mouse
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This PAOX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 467-496 amino acids from the Central region of human PAOX.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
467-496
Sequence Length
511
Applicable Applications for anti-PAOX antibody
Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(PAOX Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the PAOX antibody detected the PAOX protein (arrow).)

Western Blot (WB) (PAOX Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the PAOX antibody detected the PAOX protein (arrow).)

Western Blot (WB)

(PAOX Antibody (Center) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the PAOX antibody detected the PAOX protein (arrow).)

Western Blot (WB) (PAOX Antibody (Center) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the PAOX antibody detected the PAOX protein (arrow).)

Immunohistochemistry (IHC)

(PAOX antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PAOX antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)

Immunohistochemistry (IHC) (PAOX antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PAOX antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Product Categories/Family for anti-PAOX antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
70290
NCBI Official Full Name
peroxisomal N(1)-acetyl-spermine/spermidine oxidase isoform 1
NCBI Official Synonym Full Names
polyamine oxidase (exo-N4-amino)
NCBI Official Symbol
PAOX
NCBI Official Synonym Symbols
PAO
NCBI Protein Information
peroxisomal N(1)-acetyl-spermine/spermidine oxidase
UniProt Protein Name
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase
UniProt Gene Name
PAOX
UniProt Synonym Gene Names
PAO
UniProt Entry Name
PAOX_HUMAN

Uniprot Description

PAOX: Flavoenzyme which catalyzes the oxidation of N(1)- acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)- acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs. Belongs to the flavin monoamine oxidase family. 11 isoforms of the human protein are produced by alternative splicing.

Protein type: Oxidoreductase; EC 1.5.3.13

Chromosomal Location of Human Ortholog: 10q26.3

Cellular Component: peroxisomal matrix

Molecular Function: receptor binding; polyamine oxidase activity

Biological Process: spermine catabolic process; putrescine biosynthetic process; polyamine biosynthetic process; xenobiotic metabolic process; polyamine catabolic process; spermidine catabolic process; putrescine catabolic process; polyamine metabolic process

Research Articles on PAOX

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Product Notes

The PAOX paox (Catalog #AAA9201751) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 467-496. The PAOX Antibody (Center) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's PAOX can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the PAOX paox for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PAOX, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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