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Western Blot (WB) (Western blot analysis of PAOX expression in Jurkat (A), HT1080 (B) whole cell lysates.)

Rabbit anti-Human PAOX Polyclonal Antibody | anti-PAOX antibody

Anti-PAOX Antibody

Gene Names
PAOX; PAO
Reactivity
Human
Applications
Western Blot
Purity
The antibody was purified by immunogen affinity chromatography.
Synonyms
PAOX; Polyclonal Antibody; Anti-PAOX Antibody; PAO; Peroxisomal N(1)-acetyl-spermine/spermidine oxidase; Polyamine oxidase; anti-PAOX antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of PAOX protein.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Sequence Length
511
Applicable Applications for anti-PAOX antibody
Western Blot (WB)
Application Notes
WB (1/500 - 1/1000)
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human PAOX. The exact sequence is proprietary.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of PAOX expression in Jurkat (A), HT1080 (B) whole cell lysates.)

Western Blot (WB) (Western blot analysis of PAOX expression in Jurkat (A), HT1080 (B) whole cell lysates.)
Related Product Information for anti-PAOX antibody
Rabbit polyclonal antibody to PAOX

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
4,499 Da
NCBI Official Full Name
peroxisomal N(1)-acetyl-spermine/spermidine oxidase isoform 1
NCBI Official Synonym Full Names
polyamine oxidase (exo-N4-amino)
NCBI Official Symbol
PAOX
NCBI Official Synonym Symbols
PAO
NCBI Protein Information
peroxisomal N(1)-acetyl-spermine/spermidine oxidase; peroxisomal N(1)-acetyl-spermine/spermidine oxidase; peroxisomal N1-acetyl-spermine/spermidine oxidase
UniProt Protein Name
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase
UniProt Gene Name
PAOX
UniProt Synonym Gene Names
PAO
UniProt Entry Name
PAOX_HUMAN

Uniprot Description

PAOX: Flavoenzyme which catalyzes the oxidation of N(1)- acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)- acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs. Belongs to the flavin monoamine oxidase family. 11 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 1.5.3.13; Oxidoreductase

Chromosomal Location of Human Ortholog: 10q26.3

Cellular Component: peroxisomal matrix

Molecular Function: receptor binding; polyamine oxidase activity

Biological Process: spermine catabolic process; xenobiotic metabolic process; putrescine biosynthetic process; polyamine biosynthetic process; spermidine catabolic process; polyamine catabolic process; putrescine catabolic process; polyamine metabolic process

Research Articles on PAOX

Similar Products

Product Notes

The PAOX paox (Catalog #AAA820186) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-PAOX Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PAOX can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB (1/500 - 1/1000). Researchers should empirically determine the suitability of the PAOX paox for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PAOX, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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