Western Blot (WB)
(Western Blot; Sample: Recombinant PANX1, Rat.)
Rabbit Pannexin 1 (PANX1) Polyclonal Antibody | anti-PANX1 antibody
Polyclonal Antibody to Pannexin 1 (PANX1)
Immunohistochemistry: 5-20ug/mL
Immunocytochemistry: 5-20ug/mL
Optimal working dilutions must be determined by end user.
Avoid repeated freeze/thaw cycles.
Store at 4 degree C for frequent use.
Aliquot and store at -20 degree C for 24 months.
Stability Test:
thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Western Blot (WB)
(Western Blot; Sample: Recombinant PANX1, Rat.)
Western Blot (WB)
(Western Blot; Sample: Recombinant PANX1, Rat.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P;Samples: Rat Cardiac Muscle Tissue;Primary Ab: 20ug/ml Rabbit Anti-Rat PANX1 AntibodySecond Ab: 2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: MBS2086047 ))
Immunohistochemistry (IHC)
(DAB staining on IHC-P;Samples: Rat Cardiac Muscle Tissue;Primary Ab: 20ug/ml Rabbit Anti-Rat PANX1 AntibodySecond Ab: 2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: MBS2086047 ))
Immunohistochemistry (IHC)
(DAB staining on IHC-P;Samples: Rat Liver Tissue;Primary Ab: 20ug/ml Rabbit Anti-Rat PANX1 AntibodySecond Ab: 2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: MBS2086047 ))
Immunohistochemistry (IHC)
(DAB staining on IHC-P;Samples: Rat Liver Tissue;Primary Ab: 20ug/ml Rabbit Anti-Rat PANX1 AntibodySecond Ab: 2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: MBS2086047 ))
Immunohistochemistry (IHC)
(DAB staining on IHC-P;Samples: Rat Skin Tissue;Primary Ab: 20ug/ml Rabbit Anti-Rat PANX1 AntibodySecond Ab: 2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: MBS2086047 ))
Immunohistochemistry (IHC)
(DAB staining on IHC-P;Samples: Rat Skin Tissue;Primary Ab: 20ug/ml Rabbit Anti-Rat PANX1 AntibodySecond Ab: 2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: MBS2086047 ))
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a plasma membrane protein that is a structural component of gap junctions. The encoded protein acts as a homodimer or as a heterodimer with other isoforms or proteins. Two additional variants have been found, and the isoforms expressed from them are found in the cytoplasm. It is thought that these two isoforms could attenuate the actions of the membrane-bound protein. [provided by RefSeq, Jul 2012]
Uniprot Description
PANX1: Structural component of the gap junctions and the hemichannels. May play a role as a Ca(2+)-leak channel to regulate ER Ca(2+) homeostasis. Belongs to the pannexin family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Cell adhesion; Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 8q12
Cellular Component: endomembrane system; endoplasmic reticulum; endoplasmic reticulum membrane; gap junction; integral component of membrane; membrane; plasma membrane; protein complex
Molecular Function: actin binding; actin filament binding; calcium channel activity; channel activity; gap junction channel activity; gap junction hemi-channel activity; leak channel activity; protease binding; protein binding; protein heterodimerization activity; receptor binding
Biological Process: calcium ion transport; cation transport; cell-cell signaling; positive regulation of cytokine secretion; positive regulation of interleukin-1 alpha secretion; positive regulation of interleukin-1 beta secretion; response to ATP; transmembrane transport
Research Articles on PANX1
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Product Notes
The PANX1 panx1 (Catalog #AAA2001670) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Pannexin 1 (PANX1) reacts with Rattus norvegicus (Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's Pannexin 1 (PANX1) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB); Immunohistochemistry (IHC); Immunocytochemistry (ICC); Immunoprecipitation (IP). Western blotting: 0.5-2ug/mL Immunohistochemistry: 5-20ug/mL Immunocytochemistry: 5-20ug/mL Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the PANX1 panx1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Pannexin 1 (PANX1), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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