Western Blot (WB)
(Western Blot analysis of PAM16 in HepG2 and Jurkat cell lysates in order using PAM16 Rabbit pAb at dilution 1/700)
Rabbit anti-Human, Mouse PAM16 Polyclonal Antibody | anti-PAM16 antibody
PAM16 Rabbit pAb
Gene Names
PAM16; TIM16; MAGMAS; TIMM16; CGI-136
Reactivity
Human, Mouse
Applications
Western Blot, Immunohistochemistry
Purity
Affinity purified
Synonyms
PAM16; Polyclonal Antibody; PAM16 Rabbit pAb; presequence translocase associated motor 16; TIM16; MAGMAS; SMDMDM; TIMM16; CGI-136; anti-PAM16 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purified
Form/Format
pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration
0.9mg/ml (varies by lot)
Applicable Applications for anti-PAM16 antibody
Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P)
Application Notes
WB: 1:500-1:2000
IHC-P: 1:50-1:200
IHC-P: 1:50-1:200
Immunogen
Fusion protein of human PAM16
Conjugation
Unconjugated
Modification
Unmodified
Preparation and Storage
Store at 4 degree C for short term. Store at -20 degree C for long term. Avoid freeze/thaw cycle.
Western Blot (WB)
(Western Blot analysis of PAM16 in HepG2 and Jurkat cell lysates in order using PAM16 Rabbit pAb at dilution 1/700)
Western Blot (WB)
(Western Blot analysis of PAM16 in HepG2 and Jurkat cell lysates in order using PAM16 Rabbit pAb at dilution 1/700)
Immunohistochemistry (IHC)
(Immunohistochemistry of PAM16 in paraffin-embedded Human cervical cancer tissue using PAM16 Rabbit pAb at dilution 1/50. Predicted cell location: Cytoplasm)
Immunohistochemistry (IHC)
(Immunohistochemistry of PAM16 in paraffin-embedded Human cervical cancer tissue using PAM16 Rabbit pAb at dilution 1/50. Predicted cell location: Cytoplasm)
Related Product Information for anti-PAM16 antibody
This gene encodes a mitochondrial protein involved in granulocyte-macrophage colony-stimulating factor (GM-CSF) signaling. This protein also plays a role in the import of nuclear-encoded mitochondrial proteins into the mitochondrial matrix and may be important in reactive oxygen species (ROS) homeostasis. Mutations in this gene cause Megarbane-Dagher-Melike type spondylometaphyseal dysplasia, an early lethal skeletal dysplasia characterized by short stature, developmental delay and other skeletal abnormalities.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
13,825 Da
NCBI Official Full Name
mitochondrial import inner membrane translocase subunit TIM16
NCBI Official Synonym Full Names
presequence translocase-associated motor 16 homolog (S. cerevisiae)
NCBI Official Symbol
PAM16
NCBI Official Synonym Symbols
TIM16; MAGMAS; TIMM16; CGI-136
NCBI Protein Information
mitochondrial import inner membrane translocase subunit TIM16; magmas-like protein; mitochondria-associated granulocyte macrophage CSF-signaling molecule; mitochondria associated protein involved in granulocyte macrophage colony stimulating factor signal
UniProt Protein Name
Mitochondrial import inner membrane translocase subunit TIM16
Protein Family
UniProt Gene Name
PAM16
UniProt Synonym Gene Names
MAGMAS; TIM16; TIMM16
UniProt Entry Name
TIM16_HUMAN
Uniprot Description
Magmas: Regulates ATP-dependent protein translocation into the mitochondrial matrix. Inhibits DNAJC19 stimulation of HSPA9/Mortalin ATPase activity. Belongs to the TIM16/PAM16 family.
Protein type: Mitochondrial
Chromosomal Location of Human Ortholog: 16p13.3
Cellular Component: mitochondrial matrix; protein complex
Molecular Function: protein binding
Biological Process: cellular protein metabolic process; negative regulation of ATPase activity; ossification; protein import into mitochondrial matrix; protein targeting to mitochondrion
Disease: Spondylometaphyseal Dysplasia, Megarbane-dagher-melki Type
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Product Notes
The PAM16 pam16 (Catalog #AAA4760461) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PAM16 Rabbit pAb reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's PAM16 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P). WB: 1:500-1:2000 IHC-P: 1:50-1:200. Researchers should empirically determine the suitability of the PAM16 pam16 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PAM16, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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