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Western Blot (WB) (Western blot analysis of PAI2 antibody (Center) in NCI-H460 cell line lysates (35ug/lane). PAI2 (arrow) was detected using the purified Pab.)

Rabbit anti-Human PAI2 Polyclonal Antibody | anti-PAI2 antibody

PAI2, ID (Plasminogen Activator Inhibitor 2, PAI-2, Placental Plasminogen Activator Inhibitor, Monocyte Arg-serpin, Urokinase Inhibitor, Serpin B2, PLANH2, SERPINB2) (MaxLight 750)

Gene Names
SERPINB2; PAI; PAI2; PAI-2; PLANH2; HsT1201
Reactivity
Human
Applications
Western Blot
Purity
Purified by Ammonium Sulfate Precipitation.
Synonyms
PAI2; Polyclonal Antibody; ID (Plasminogen Activator Inhibitor 2; PAI-2; Placental Plasminogen Activator Inhibitor; Monocyte Arg-serpin; Urokinase Inhibitor; Serpin B2; PLANH2; SERPINB2) (MaxLight 750); anti-PAI2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human PAI2.
Purity/Purification
Purified by Ammonium Sulfate Precipitation.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight750.
Applicable Applications for anti-PAI2 antibody
Western Blot (WB), FLISA
Application Notes
WB: 1:50-1:100
FLISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
Synthetic peptide selected from the center region of human PAI2 (KLH).
Conjugate
MaxLight750
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight750 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(Western blot analysis of PAI2 antibody (Center) in NCI-H460 cell line lysates (35ug/lane). PAI2 (arrow) was detected using the purified Pab.)

Western Blot (WB) (Western blot analysis of PAI2 antibody (Center) in NCI-H460 cell line lysates (35ug/lane). PAI2 (arrow) was detected using the purified Pab.)

Immunohistochemistry (IHC)

(PAI2 Antibody (Center) IHC analysis in formalin fixed and paraffin embedded mouse brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PAI2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)

Immunohistochemistry (IHC) (PAI2 Antibody (Center) IHC analysis in formalin fixed and paraffin embedded mouse brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PAI2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Product Categories/Family for anti-PAI2 antibody
References
1. Di Bernardo, M.C., Lung Cancer 65(2), 237-241 (2009). 2. Almeida-Vega, S., Am. J. Physiol. Gastrointest. Liver Physiol. 296(2), G414-G423 (2009).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
46,596 Da
NCBI Official Full Name
plasminogen activator inhibitor 2
NCBI Official Synonym Full Names
serpin peptidase inhibitor, clade B (ovalbumin), member 2
NCBI Official Symbol
SERPINB2
NCBI Official Synonym Symbols
PAI; PAI2; PAI-2; PLANH2; HsT1201
NCBI Protein Information
plasminogen activator inhibitor 2
UniProt Protein Name
Plasminogen activator inhibitor 2
UniProt Gene Name
SERPINB2
UniProt Synonym Gene Names
PAI2; PLANH2; PAI-2
UniProt Entry Name
PAI2_HUMAN

Uniprot Description

SERPINB2: Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell- derived PAI-1. Belongs to the serpin family. Ov-serpin subfamily.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 18q21.3

Cellular Component: extracellular space; cytoplasm; extracellular region; plasma membrane

Molecular Function: serine-type endopeptidase inhibitor activity

Biological Process: fibrinolysis; blood coagulation; negative regulation of apoptosis

Research Articles on PAI2

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Product Notes

The PAI2 serpinb2 (Catalog #AAA6493710) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PAI2, ID (Plasminogen Activator Inhibitor 2, PAI-2, Placental Plasminogen Activator Inhibitor, Monocyte Arg-serpin, Urokinase Inhibitor, Serpin B2, PLANH2, SERPINB2) (MaxLight 750) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PAI2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), FLISA. WB: 1:50-1:100 FLISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the PAI2 serpinb2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PAI2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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