Western Blot (WB)
(Sample Data: Western blot on transformed U2OS and HeLa cell lysates and control (-) using Anti-p29ING4 at 1.0 ug/ml)
Goat anti-Human p29ING4 Polyclonal Antibody | anti-p29ING4 antibody
Anti-p29ING4
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Immunoaffinity chromatography
Synonyms
p29ING4; Polyclonal Antibody; Anti-p29ING4; anti-p29ING4 antibody
Host
Goat
Reactivity
Human
Clonality
Polyclonal
Isotype
Goat, IgG
Specificity
Recognizes the p29 ING4 protein
Purity/Purification
Immunoaffinity chromatography
Form/Format
0.02M Potassium Phosphate, 0.15M Sodium Chloride, pH7.2 + 0.01% (w/v) Sodium Azide
Applicable Applications for anti-p29ING4 antibody
ELISA (EIA), Western Blot (WB)
Immunogen
The antibody was produced against synthesized peptide corresponding to amino acids 164-175 of human p29 ING4 protein (inhibitor of growth family, member 4)
Preparation and Storage
1 year at -20 degree C from date of shipment
Western Blot (WB)
(Sample Data: Western blot on transformed U2OS and HeLa cell lysates and control (-) using Anti-p29ING4 at 1.0 ug/ml)
Western Blot (WB)
(Sample Data: Western blot on transformed U2OS and HeLa cell lysates and control (-) using Anti-p29ING4 at 1.0 ug/ml)
Related Product Information for anti-p29ING4 antibody
p29 ING4 is a tumor suppressor protein similar to ING1 that may inhibit tumor progression by modulating the transcriptional output of signaling pathways which regulate cell proliferation. p29 ING4 has been shown to suppress brain tumor angio-genesis through transcriptional repression of RelA/ NFKB3 target genes when complexed with RelA. p29 ING4 may also specifically suppress loss of contact inhibition elicited by activated oncogenes such as MYC. p29 ING4 shows a nuclear localization and interacts with EP300, TP53, RelA, inhibits cell growth, and induces apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. Multiple alternatively spliced transcript variants have been observed. The accession number listed below is for variant (1) that encodes the longest isoform.
Product Categories/Family for anti-p29ING4 antibody
References
1. Shiseki,M., et al.: p29ING4 and p28ING5 bind to p53 and p300, and enhance p53 activity. Cancer Res. 2003: 63 (10); 2373-2378.
2. Zhang,X., et al.: ING4 induces G2/M cell cycle arrest and enhances the chemosensitivity to DNA-damage agents in HepG2 cells. FEBS Lett. 2004: 570 (1-3); 7-12.
3. Garkavtsev,I., et al.: The candidate tumour suppressor protein ING4 regulates brain tumour growth and angiogenesis. Nature. 2004: 428 (6980); 328-332.
2. Zhang,X., et al.: ING4 induces G2/M cell cycle arrest and enhances the chemosensitivity to DNA-damage agents in HepG2 cells. FEBS Lett. 2004: 570 (1-3); 7-12.
3. Garkavtsev,I., et al.: The candidate tumour suppressor protein ING4 regulates brain tumour growth and angiogenesis. Nature. 2004: 428 (6980); 328-332.
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Product Notes
The p29ING4 (Catalog #AAA516024) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Anti-p29ING4 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's p29ING4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Researchers should empirically determine the suitability of the p29ING4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "p29ING4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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