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Western Blot (WB)

Rabbit A1Up Polyclonal Antibody | anti-A1Up antibody

A1Up Antibody

Gene Names
UBQLN4; A1U; A1Up; UBIN; CIP75; C1orf6
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Synonyms
A1Up; Polyclonal Antibody; A1Up Antibody; UBQLN4; A1U; C1orf6; CIP75; UBIN; Ubiquilin 4; Ubiquilin-4; anti-A1Up antibody
Ordering
 
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For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
A1Up Antibody detects endogenous levels of total A1Up
Form/Format
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0mg/mL (varies by lot)
Sequence Length
581
Applicable Applications for anti-A1Up antibody
Western Blot (WB)
Application Notes
Western Blot: 1:1000
Immunogen
A synthesized peptide derived from human A1Up
Immunogen Type
Peptide
Preparation and Storage
Store at -20 degree C

Western Blot (WB)

(Western blot analysis A1Up using COLO205 whole cell lysates)

Product Categories/Family for anti-A1Up antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
24,527 Da
NCBI Official Full Name
ubiquilin-4 isoform 2
NCBI Official Synonym Full Names
ubiquilin 4
NCBI Official Symbol
UBQLN4
NCBI Official Synonym Symbols
A1U; A1Up; UBIN; CIP75; C1orf6
NCBI Protein Information
ubiquilin-4
UniProt Protein Name
Ubiquilin-4
UniProt Gene Name
UBQLN4
UniProt Synonym Gene Names
C1orf6; CIP75; UBIN; A1Up; CIP75
UniProt Entry Name
UBQL4_HUMAN

Uniprot Description

UBQLN4: Plays a role in the regulation of proteasomal protein degradation. Depending on the case, may promote or inhibit proteasomal protein degradation. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 1q21

Cellular Component: autophagic vacuole; cytoplasm; cytosol; endoplasmic reticulum membrane; nucleus

Molecular Function: identical protein binding; polyubiquitin binding; protein binding

Biological Process: regulation of proteasomal ubiquitin-dependent protein catabolic process

Research Articles on A1Up

1. results suggested that CIP75 is essential for the interaction of Cx43 and the proteasome, but that alternate compensatory mechanisms exist to supplement the degradation normally facilitated by CIP75

Similar Products

A1Up Antibody

Host: n/a
Reactivity: n/a
Apps: n/a

UBQLN4 Antibody

Host: Rabbit
Reactivity: Human
Apps: Western Blot

CIP75 Antibody

Host: Rabbit
Reactivity: Human, Mouse, Rat
Apps: ELISA, Western Blot, Immunohistochemistry

Product Notes

The A1Up ubqln4 (Catalog #AAA9417676) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The A1Up Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's A1Up can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot: 1:1000. Researchers should empirically determine the suitability of the A1Up ubqln4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "A1Up, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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