Rabbit p19 INK4d Polyclonal Antibody | anti-INK4D antibody

p19 INK4d Polyclonal Antibody

Cat. Num. AAA2556367

• Gene Names: CDKN2D; p19; INK4D; p19-INK4D
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot
• Purity: Affinity Purification
• Synonyms: p19 INK4d; Polyclonal Antibody; p19 INK4d Polyclonal Antibody; CDK inhibitor p19INK4d; CDKN2D; Cyclin dependent kinase inhibitor 2D; Cyclin-dependent kinase 4 inhibitor D; Cyclin-dependent kinase inhibitor 2D (p19; inhibits CDK4); inhibitor of cyclin-dependent kinase 4d; MGC109660; MGC137547; MGC73010; p19; p19-INK4D; p19INK4d; Similar to cyclin-dependent kinase inhibitor 2D; anti-INK4D antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity Purification
• Form/Format: PBS with 0.02% sodium azide, 100 mug/ml BSA and 50% glycerol.
• Concentration: 2.6 mg/mL (varies by lot)
• Sequence Length: 166

• Applicable Applications for anti-INK4D antibody: Western Blot (WB)
• Application Notes: WB: 1:500
• Immunogen: KLH conjugated synthetic peptide corresponding to Mouse p19 INK4d
• Conjugation: Unconjugated
• Preparation and Storage: Store at -20 degree C. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western Blot analysis of various samples using p19 INK4d Polyclonal Antibody at dilution of 1:500.)

Related Product Information for anti-INK4D antibody

The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis. Two alternatively spliced variants of this gene, which encode an identical protein, have been reported.

Product Categories/Family for anti-INK4D antibody

Cancer; Cell Biology; Epigenetics and Nuclear Signaling

NCBI and Uniprot Product Information

• NCBI GI #: 4502753
• NCBI GeneID: 1032
• NCBI Accession #: NP_001791.1
• NCBI GenBank Nucleotide #: NM_001800.3
• UniProt Accession #: P55273; Q13102; Q6FGE9
• Molecular Weight: Calculated: 19kDa; Observed: 19kDa
• NCBI Official Full Name: cyclin-dependent kinase 4 inhibitor D
• NCBI Official Synonym Full Names: cyclin dependent kinase inhibitor 2D
• NCBI Official Symbol: CDKN2D
• NCBI Official Synonym Symbols: p19; INK4D; p19-INK4D
• NCBI Protein Information: cyclin-dependent kinase 4 inhibitor D
• UniProt Protein Name: Cyclin-dependent kinase 4 inhibitor D
• UniProt Gene Name: CDKN2D

NCBI Description

The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis. Two alternatively spliced variants of this gene, which encode an identical protein, have been reported. [provided by RefSeq, Jul 2008]

Uniprot Description

Interacts strongly with CDK4 and CDK6 and inhibits them.