Rabbit anti-Human OXCT1 Polyclonal Antibody | anti-OXCT1 antibody

OXCT1 (3-oxoacid CoA Transferase 1, OXCT, SCOT) (Biotin)

Cat. Num. AAA6451313

• Gene Names: OXCT1; OXCT; SCOT
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified
• Synonyms: OXCT1; Polyclonal Antibody; OXCT1 (3-oxoacid CoA Transferase 1; OXCT; SCOT) (Biotin); 3-oxoacid CoA Transferase 1; SCOT; anti-OXCT1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human OXCT1.
• Purity/Purification: Purified
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.

• Applicable Applications for anti-OXCT1 antibody: Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: OXCT1 (NP_000427.1, 1aa-520aa) full-length human protein.
• Immunogen Sequence: MAALKLLSSGLRLCASARGSGATWYKGCVCSFSTSAHRHTKFYTDPVEAVKDIPDGATVLVGGFGLCGIPENLIDALLKTGVKGLTAVSNNAGVDNFGLGLLLRSKQIKRMVSSYVGENAEFERQYLSGELEVELTPQGTLAERIRAGGAGVPAFYTPTGYGTLVQEGGSPIKYNKDGSVAIASKPREVREFNGQHFILEEAITGDFALVKAWKADRAGNVIFRKSARNFNLPMCKAAETTVVEVEEIVDIGAFAPEDIHIPQIYVHRLIKGEKYEKRIERLSIRKEGDGEAKSAKPGDDVRERIIKRAALEFEDGMYANLGIGIPLLASNFISPNITVHLQSENGVLGLGPYPRQHEADADLINAGKETVTILPGASFFSSDESFAMIRGGHVDLTMLGAMQVSKYGDLANWMIPGKMVKGMGGAMDLVSSAKTKVVVTMEHSAKGNAHKIMEKCTLPLTGKQCVNRIITEKAVFDVDKKKGLTLIELWEGLTVDDVQKSTGCDFAVSPKLMPMQQIAN
• Conjugate: Biotin
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(OXCT1 MaxPab rabbit polyclonal antibody. Western Blot analysis of OXCT1 expression in Jurkat.)

Western Blot (WB)

(OXCT1 MaxPab rabbit polyclonal antibody. Western Blot analysis of OXCT1 expression in HeLa.)

Western Blot (WB)

(OXCT1 MaxPab rabbit polyclonal antibody. Western Blot analysis of OXCT1 expression in NIH/3T3.)

Product Categories/Family for anti-OXCT1 antibody

Antibodies; Coenzyme A

NCBI and Uniprot Product Information

• NCBI GI #: 4557817
• NCBI GeneID: 5019
• NCBI Accession #: NP_000427.1
• NCBI GenBank Nucleotide #: NM_000436.3
• UniProt Accession #: P55809; B2R5V2; B7Z528
• Molecular Weight: 13,358 Da
• NCBI Official Full Name: succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial
• NCBI Official Synonym Full Names: 3-oxoacid CoA-transferase 1
• NCBI Official Symbol: OXCT1
• NCBI Official Synonym Symbols: OXCT; SCOT
• NCBI Protein Information: succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial
• UniProt Protein Name: Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial
• Protein Family: Succinyl-CoA:3-ketoacid coenzyme A transferase
• UniProt Gene Name: OXCT1
• UniProt Synonym Gene Names: OXCT; SCOT; SCOT-s

NCBI Description

This gene encodes a member of the 3-oxoacid CoA-transferase gene family. The encoded protein is a homodimeric mitochondrial matrix enzyme that plays a central role in extrahepatic ketone body catabolism by catalyzing the reversible transfer of coenzyme A from succinyl-CoA to acetoacetate. Mutations in this gene are associated with succinyl CoA:3-oxoacid CoA transferase deficiency. [provided by RefSeq, Jul 2008]

Uniprot Description

Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.