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Western Blot (WB) (Opticin antibody (MBS5300086) used at 1 ug/ml to detect target protein.)

Rabbit Opticin Polyclonal Antibody | anti-OPTC antibody

Opticin antibody

Gene Names
OPTC; OPT
Applications
Western Blot
Purity
Affinity purified
Synonyms
Opticin; Polyclonal Antibody; Opticin antibody; Polyclonal Opticin; Anti-Opticin; OPT; OPTC; anti-OPTC antibody
Ordering
For Research Use Only!
Host
Rabbit
Clonality
Polyclonal
Specificity
Opticin antibody was raised against the C terminal of OPTC
Purity/Purification
Affinity purified
Form/Format
Lyophilized powder. Add 50ul distilled water for a 1mg/ml concentration of OPTC antibody in PBS
Concentration
1 mg/ml (varies by lot)
Sequence Length
332
Applicable Applications for anti-OPTC antibody
Western Blot (WB)
Application Notes
WB: 1 ug/ml
Biological Significance
Opticin belongs to class III of the small leucine-rich repeat protein (SLRP) family. Members of this family are typically associated with the extracellular matrix. Opticin is present in significant quantities in the vitreous of the eye and also ocalizes to the cornea, iris, ciliary body, optic nerve, choroid, retina, and fetal liver. Opticin may noncovalently bind collagen fibrils and regulate fibril morphology, spacing, and organization.
Cross-Reactivity
Human
Immunogen
Opticin antibody was raised using the C terminal of OPTC corresponding to a region with amino acids LSDNLLDSIPGPLPLSLRSVHLQNNLIETMQRDVFCDPEEHKHTRRQLED
Preparation and Storage
Store at 2-8 degree C for short periods. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.

Western Blot (WB)

(Opticin antibody (MBS5300086) used at 1 ug/ml to detect target protein.)

Western Blot (WB) (Opticin antibody (MBS5300086) used at 1 ug/ml to detect target protein.)
Related Product Information for anti-OPTC antibody
Rabbit polyclonal Opticin antibody raised against the C terminal of OPTC
Product Categories/Family for anti-OPTC antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
35 kDa (MW of target protein)
NCBI Official Full Name
opticin
NCBI Official Synonym Full Names
opticin
NCBI Official Symbol
OPTC
NCBI Official Synonym Symbols
OPT
NCBI Protein Information
opticin
UniProt Protein Name
Opticin
Protein Family
UniProt Gene Name
OPTC
UniProt Synonym Gene Names
OPT
UniProt Entry Name
OPT_HUMAN

NCBI Description

Opticin belongs to class III of the small leucine-rich repeat protein (SLRP) family. Members of this family are typically associated with the extracellular matrix. Opticin is present in significant quantities in the vitreous of the eye and also localizes to the cornea, iris, ciliary body, optic nerve, choroid, retina, and fetal liver. Opticin may noncovalently bind collagen fibrils and regulate fibril morphology, spacing, and organization. The opticin gene is mapped to a region of chromosome 1 that is associated with the inherited eye diseases age-related macular degeneration (AMD) and posterior column ataxia with retinosa pigmentosa (AXPC1). [provided by RefSeq, Jul 2008]

Uniprot Description

OPTC: Binds collagen fibrils. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 1q32.1

Cellular Component: proteinaceous extracellular matrix

Molecular Function: extracellular matrix structural constituent

Biological Process: negative regulation of angiogenesis

Research Articles on OPTC

Similar Products

Product Notes

The OPTC optc (Catalog #AAA5300086) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Opticin can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1 ug/ml. Researchers should empirically determine the suitability of the OPTC optc for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Opticin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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