Rabbit anti-Human ONECUT2 Polyclonal Antibody | anti-ONECUT2 antibody
ONECUT2, NT (ONECUT2, HNF6B, One cut domain family member 2, Hepatocyte nuclear factor 6-beta, One cut homeobox 2, Transcription factor ONECUT-2)
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the onecut family of transcription factors, which are characterized by a cut domain and an atypical homeodomain. The protein binds to specific DNA sequences and stimulates expression of target genes, including genes involved in melanocyte and hepatocyte differentiation. [provided by RefSeq, Jul 2008]
Uniprot Description
ONECUT2: Transcriptional activator. Activates the transcription of a number of liver genes such as HNF3B. Belongs to the CUT homeobox family.
Protein type: Transcription factor; DNA-binding; Cell development/differentiation; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 18q21.31
Cellular Component: nucleoplasm; actin cytoskeleton
Biological Process: cell fate commitment; transcription, DNA-dependent; regulation of cell-matrix adhesion; liver development; endocrine pancreas development; peripheral nervous system neuron development; organ morphogenesis; cilium biogenesis; epithelial cell development; positive regulation of transcription from RNA polymerase II promoter; cell differentiation; negative regulation of transforming growth factor beta receptor signaling pathway; positive regulation of cell migration
Research Articles on ONECUT2
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Product Notes
The ONECUT2 onecut2 (Catalog #AAA6000636) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ONECUT2, NT (ONECUT2, HNF6B, One cut domain family member 2, Hepatocyte nuclear factor 6-beta, One cut homeobox 2, Transcription factor ONECUT-2) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ONECUT2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in Western Blot, ELISA Dilution: ELISA: 1:1,000 Western Blot: 1:100-500. Researchers should empirically determine the suitability of the ONECUT2 onecut2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ONECUT2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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