Western Blot (WB)
(Western blot analysis of Oma1 expression in K562 (A), mouse liver (B) whole cell lysates.)
Rabbit Oma1 Polyclonal Antibody | anti-OMA1 antibody
Anti-Oma1 Antibody
Western Blot (WB)
(Western blot analysis of Oma1 expression in K562 (A), mouse liver (B) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of Oma1 expression in K562 (A), mouse liver (B) whole cell lysates.)
NCBI and Uniprot Product Information
Uniprot Description
OMA1: Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of OPA1 at S1 position, leading to OPA1 inactivation and negative regulation of mitochondrial fusion. Its role in mitochondrial quality control is essential for regulating lipid metabolism as well as to maintain body temperature and energy expenditure under cold-stress conditions. Belongs to the peptidase M48 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Membrane protein, integral; Protease; EC 3.4.24.-
Chromosomal Location of Human Ortholog: 1p32.2-p32.1
Cellular Component: mitochondrial membrane; mitochondrial inner membrane; integral to membrane
Molecular Function: metalloendopeptidase activity; metal ion binding
Biological Process: diet induced thermogenesis; cristae formation; misfolded or incompletely synthesized protein catabolic process; response to stress; glucose metabolic process; lipid metabolic process
Research Articles on OMA1
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Product Notes
The OMA1 oma1 (Catalog #AAA8307541) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Oma1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Oma1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the OMA1 oma1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Oma1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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