Rabbit anti-Human Obestatin Polyclonal Antibody
Anti-Obestatin (Appetite-regulating Hormone, Growth Hormone Secretagogue, Growth Hormone-releasing Peptide, Motilin-related Peptide, Protein M46, Ghrelin, GHRL, MTLRP, UNQ524/PRO1066)
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Serum
Synonyms
Obestatin; Polyclonal Antibody; Anti-Obestatin (Appetite-regulating Hormone; Growth Hormone Secretagogue; Growth Hormone-releasing Peptide; Motilin-related Peptide; Protein M46; Ghrelin; GHRL; MTLRP; UNQ524/PRO1066); Appetite-regulating Hormone; UNQ524/PRO1066; anti-Obestatin antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
Recognizes human Obestatin.
Purity/Purification
Serum
Form/Format
Supplied as a liquid in PBS, 0.05% sodium azide.
Applicable Applications for anti-Obestatin antibody
ELISA; Western Blot
Application Notes
Recommended Dilutions: ELISA: 1:100,000
Western Blot: 1-10ug/ml
Western Blot: 1-10ug/ml
Immunogen
Synthetic peptide corresponding to 13aa of human OBSN1 (Accession #Q9UBU3), N-terminal, extracellular (KLH).
Source Information
Human
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Shipping Temperature: Blue Ice
Shipping Temperature: Blue Ice
Related Product Information for anti-Obestatin antibody
Control of appetite involves a number of gastrointestinal hormones that belong to the ghrelin-motilin ligand family that either stimulate food intake and gastric emptying or inhibit these responses.
Recently, a new member of the ghrelin-motilin family was identified by using bioinformatic predictions about enzyme cleavage of the prepropeptide of ghrelin. The newly identified 23aa, ghrelin-associated peptide was named obestatin. Although both peptides originate from the same precursor prepropeptide, they have opposing physiological roles. Obestatin exerts anorexigenic effects by decreasing food intake, gastric emptying, jejunal motility, and weight gain by binding to GPR39 orphan receptor, while ghrelin exerts opposing orexigenic effects by binding to growth hormone secretagogue receptor. Reports that GPR39 is a cognate receptor for Obestatin were recently contradicted warning for more prudent approach to investigation.
Recently, a new member of the ghrelin-motilin family was identified by using bioinformatic predictions about enzyme cleavage of the prepropeptide of ghrelin. The newly identified 23aa, ghrelin-associated peptide was named obestatin. Although both peptides originate from the same precursor prepropeptide, they have opposing physiological roles. Obestatin exerts anorexigenic effects by decreasing food intake, gastric emptying, jejunal motility, and weight gain by binding to GPR39 orphan receptor, while ghrelin exerts opposing orexigenic effects by binding to growth hormone secretagogue receptor. Reports that GPR39 is a cognate receptor for Obestatin were recently contradicted warning for more prudent approach to investigation.
Product Categories/Family for anti-Obestatin antibody
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Product Notes
The Obestatin (Catalog #AAA624936) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Obestatin (Appetite-regulating Hormone, Growth Hormone Secretagogue, Growth Hormone-releasing Peptide, Motilin-related Peptide, Protein M46, Ghrelin, GHRL, MTLRP, UNQ524/PRO1066) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Obestatin can be used in a range of immunoassay formats including, but not limited to, ELISA; Western Blot. Recommended Dilutions: ELISA: 1:100,000 Western Blot: 1-10ug/ml. Researchers should empirically determine the suitability of the Obestatin for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Obestatin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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