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Testing Data

Rabbit anti-Human Nucleostemin Polyclonal Antibody | anti-GNL3 antibody

Nucleostemin Antibody

Gene Names
GNL3; NS; E2IG3; NNP47; C77032
Reactivity
Human
Applications
ELISA, Western Blot
Synonyms
Nucleostemin; Polyclonal Antibody; Nucleostemin Antibody; anti-GNL3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Form/Format
Purified by peptide affinity column containing 1% BSA and 0.02% NaN3
Sequence Length
549
Applicable Applications for anti-GNL3 antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes
Peptide ELISA: 1:40,000-1:80,000
WB: 1:200-1,000
Preparation and Storage
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C.

Testing Data

Testing Data
Related Product Information for anti-GNL3 antibody
Rabbit polyclonal Nucleostemin (1) antibody was raised against a 16 amino acid peptide from near the intermediate of human Nucleostemin protein.
References
(1) Han, C., Zhang, X., Xu, W., et al. Cloning of the nucleostemin gene and its function in transforming human embryonic bone marrow mesenchymal stem cells into F6 tumor cells Int. J. Mol. Med. 16 (2), 205-213 (2005).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
60,540 Da
NCBI Official Full Name
nucleostemin
NCBI Official Synonym Full Names
G protein nucleolar 3
NCBI Official Symbol
GNL3
NCBI Official Synonym Symbols
NS; E2IG3; NNP47; C77032
NCBI Protein Information
guanine nucleotide-binding protein-like 3
UniProt Protein Name
Guanine nucleotide-binding protein-like 3
UniProt Gene Name
GNL3
UniProt Synonym Gene Names
E2IG3; NS; NNP47

NCBI Description

The protein encoded by this gene may interact with p53 and may be involved in tumorigenesis. The encoded protein also appears to be important for stem cell proliferation. This protein is found in both the nucleus and nucleolus. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]

Uniprot Description

May be required to maintain the proliferative capacity of stem cells. Stabilizes MDM2 by preventing its ubiquitination, and hence proteasomal degradation ().

Research Articles on GNL3

Similar Products

Product Notes

The GNL3 gnl3 (Catalog #AAA851471) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Nucleostemin Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Nucleostemin can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB). Peptide ELISA: 1:40,000-1:80,000 WB: 1:200-1,000. Researchers should empirically determine the suitability of the GNL3 gnl3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Nucleostemin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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