Western Blot (WB)
(Western blot analysis of Nucleobindin 2 expression in HEPA whole cell lysates (lane 1). Nucleobindin 2 at 55KD was detected using rabbit anti- Nucleobindin 2 Antigen Affinity purified polyclonal antibody at0.5ug/mL. The blot was developed using chemiluminescence (ECL) method. )
anti-Mouse, Rat Nucleobindin 2 Polyclonal Antibody | anti-Nucb2 antibody
Anti-Nucleobindin 2 Antibody
Western Blot Concentration: 0.1-0.5ug/ml
Immunohistochemistry (IHC) Paraffin Concentration: 0.5-1ug/ml
Western Blot (WB)
(Western blot analysis of Nucleobindin 2 expression in HEPA whole cell lysates (lane 1). Nucleobindin 2 at 55KD was detected using rabbit anti- Nucleobindin 2 Antigen Affinity purified polyclonal antibody at0.5ug/mL. The blot was developed using chemiluminescence (ECL) method. )
Western Blot (WB)
(Western blot analysis of Nucleobindin 2 expression in HEPA whole cell lysates (lane 1). Nucleobindin 2 at 55KD was detected using rabbit anti- Nucleobindin 2 Antigen Affinity purified polyclonal antibody at0.5ug/mL. The blot was developed using chemiluminescence (ECL) method. )
Immunohistochemistry (IHC)
(Nucleobindin 2 was detected in paraffin-embedded sections of mouse gaster tissues using rabbit anti- Nucleobindin 2 Antigen Affinity purified polyclonal antibody at 1 ug/mL. The immunohistochemical section was developed using SABC method. )
Immunohistochemistry (IHC)
(Nucleobindin 2 was detected in paraffin-embedded sections of mouse gaster tissues using rabbit anti- Nucleobindin 2 Antigen Affinity purified polyclonal antibody at 1 ug/mL. The immunohistochemical section was developed using SABC method. )
Immunohistochemistry (IHC)
(Nucleobindin 2 was detected in paraffin-embedded sections of rat gaster tissues using rabbit anti- Nucleobindin 2 Antigen Affinity purified polyclonal antibody at 1ug/mL. The immunohistochemical section was developed using SABC method. )
Immunohistochemistry (IHC)
(Nucleobindin 2 was detected in paraffin-embedded sections of rat gaster tissues using rabbit anti- Nucleobindin 2 Antigen Affinity purified polyclonal antibody at 1ug/mL. The immunohistochemical section was developed using SABC method. )
Background: Nucleobindin-2 is a calcium-binding EF-hand protein that in humans is encoded by the NUCB2 gene. By exon trapping and sequence analysis, the NUCB2 sequence has been identified on chromosome 11p15-p14. This gene encodes a protein with a suggested role in calcium level maintenance, eating regulation in the hypothalamus, and release of tumor necrosis factor from vascular endothelial cells.
NCBI and Uniprot Product Information
Uniprot Description
NUCB2: Calcium-binding protein. May have a role in calcium homeostasis. Belongs to the nucleobindin family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted; Vesicle; Secreted, signal peptide
Cellular Component: cytoplasm; endoplasmic reticulum; ER-Golgi intermediate compartment; extracellular region; extracellular space; Golgi apparatus; Golgi medial cisterna; membrane; nuclear outer membrane; nucleus
Molecular Function: calcium ion binding; DNA binding; metal ion binding; tumor necrosis factor receptor binding
Biological Process: cellular calcium ion homeostasis; negative regulation of appetite; negative regulation of cAMP biosynthetic process; negative regulation of fat cell differentiation; negative regulation of insulin receptor signaling pathway; positive regulation of fatty acid oxidation
Research Articles on Nucb2
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Product Notes
The Nucb2 nucb2 (Catalog #AAA177786) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Anti-Nucleobindin 2 Antibody reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Nucleobindin 2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA). ELISA Concentration: 0.1-0.5ug/ml Western Blot Concentration: 0.1-0.5ug/ml Immunohistochemistry (IHC) Paraffin Concentration: 0.5-1ug/ml. Researchers should empirically determine the suitability of the Nucb2 nucb2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Nucleobindin 2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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