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Western Blot (WB) (Western blot analysis of extracts of various cell lines, using NUAK2 antibody.)

Rabbit NUAK2 Polyclonal Antibody | anti-NUAK2 antibody

NUAK2 antibody

Gene Names
NUAK2; SNARK
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
Antibodies were purified by affinity purification using immunogen.
Synonyms
NUAK2; Polyclonal Antibody; NUAK2 antibody; DKFZp434J037; DKFZp686F01113; FLJ90349; SNARK; anti-NUAK2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
The antibody detects endogenous level of total NUAK2 antibody.
Purity/Purification
Antibodies were purified by affinity purification using immunogen.
Form/Format
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
672
Applicable Applications for anti-NUAK2 antibody
Western Blot (WB)
Application Notes
Western blotting: 1:500 - 1:2000
Immunogen Type
Recombinant Protein
Immunogen Description
Recombinant protein of human NUAK2.
Target Name
NUAK2
Preparation and Storage
Store at -20 degree C

Western Blot (WB)

(Western blot analysis of extracts of various cell lines, using NUAK2 antibody.)

Western Blot (WB) (Western blot analysis of extracts of various cell lines, using NUAK2 antibody.)
Related Product Information for anti-NUAK2 antibody
SNARK was identified as an SNF1/AMPK-related kinase and member of the AMPK catalytic subunit family (1,2). This enzyme was separately identified as a TNFa-induced SNF1-like kinase 2 (NUAK2) (3). The kinase activity of SNARK/NUAK2 is increased by AMP and AICAR (1). SNARK/NUAK2 activity is regulated by a variety of cellular stresses such as endoplasmic reticulum (ER) stress and oxidative stresses (4), suggesting that SNARK/NUAK2 is a signaling molecule involved in the cell stress response (4).
Product Categories/Family for anti-NUAK2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
69,612 Da
NCBI Official Full Name
NUAK family SNF1-like kinase 2
NCBI Official Synonym Full Names
NUAK family, SNF1-like kinase, 2
NCBI Official Symbol
NUAK2
NCBI Official Synonym Symbols
SNARK
NCBI Protein Information
NUAK family SNF1-like kinase 2
UniProt Protein Name
NUAK family SNF1-like kinase 2
UniProt Gene Name
NUAK2
UniProt Synonym Gene Names
SNARK
UniProt Entry Name
NUAK2_HUMAN

Uniprot Description

NuaK2: a Ca(2+)/calmodulin-dependent protein kinase of the CAMKL family.

Protein type: Protein kinase, CAMK; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; EC 2.7.11.1; CAMK group; CAMKL family; NuaK subfamily

Chromosomal Location of Human Ortholog: 1q32.1

Molecular Function: protein serine/threonine kinase activity; protein binding; magnesium ion binding; ATP binding

Biological Process: cellular response to glucose starvation; apoptosis; actin cytoskeleton organization and biogenesis; protein amino acid phosphorylation; negative regulation of apoptosis

Research Articles on NUAK2

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Product Notes

The NUAK2 nuak2 (Catalog #AAA9409950) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NUAK2 antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's NUAK2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western blotting: 1:500 - 1:2000. Researchers should empirically determine the suitability of the NUAK2 nuak2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NUAK2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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