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Western Blot (WB) (Western blot analysis of extracts from Jurkat cells using NTR2 antibody)

Rabbit NTR2 Polyclonal Antibody | anti-NTR2 antibody

NTR2 antibody

Gene Names
NTSR2; NTR2
Applications
Western Blot, Immunofluorescence, ELISA
Synonyms
NTR2; Polyclonal Antibody; NTR2 antibody; Polyclonal NTR2; Anti-NTR2; NTS2 receptor; levocabastine-sensitive neurotensin receptor; anti-NTR2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Specificity
NTR2 antibody detects endogenous levels of total NTR2 protein
Form/Format
Purified IgG in PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
Concentration
1 mg/ml (varies by lot)
Sequence Length
410
Applicable Applications for anti-NTR2 antibody
Western Blot (WB), Immunofluorescence (IF), ELISA (EIA)
Application Notes
WB: 1:500-1:1000
IF: 1:100-1:500
ELISA: 1:40000
Biological Significance
Neurotensin (NT) initiates an intracellular response by interacting with the G protein-coupled receptors NTR1 (NTS1 receptor, high affinity NTR) and NTR2.
Cross-Reactivity
Mouse, Rat
Immunogen
NTR2 antibody was raised in Rabbit using a synthesized peptide derived from internal of human NTR2 as the immunogen
Preparation and Storage
Store at -20 degree C in small aliquots. Avoid repeated freeze-thaw cycles

Western Blot (WB)

(Western blot analysis of extracts from Jurkat cells using NTR2 antibody)

Western Blot (WB) (Western blot analysis of extracts from Jurkat cells using NTR2 antibody)
Related Product Information for anti-NTR2 antibody
Rabbit polyclonal NTR2 antibody
Product Categories/Family for anti-NTR2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
45,385 Da
NCBI Official Full Name
neurotensin receptor type 2
NCBI Official Synonym Full Names
neurotensin receptor 2
NCBI Official Symbol
NTSR2
NCBI Official Synonym Symbols
NTR2
NCBI Protein Information
neurotensin receptor type 2
UniProt Protein Name
Neurotensin receptor type 2
Protein Family
UniProt Gene Name
NTSR2
UniProt Synonym Gene Names
NT-R-2; NTR2
UniProt Entry Name
NTR2_HUMAN

NCBI Description

The protein encoded by this gene belongs to the G protein-coupled receptor family that activate a phosphatidylinositol-calcium second messenger system. Binding and pharmacological studies demonstrate that this receptor binds neurotensin as well as several other ligands already described for neurotensin NT1 receptor. However, unlike NT1 receptor, this gene recognizes, with high affinity, levocabastine, a histamine H1 receptor antagonist previously shown to compete with neurotensin for low-affinity binding sites in brain. These activities suggest that this receptor may be of physiological importance and that a natural agonist for the receptor may exist. [provided by RefSeq, Jul 2008]

Uniprot Description

NTSR2: neurotensin receptor 2

Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 2p25.1

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; neurotensin receptor activity, G-protein coupled

Biological Process: regulation of membrane potential; cell surface receptor linked signal transduction; neuropeptide signaling pathway; sensory perception; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)

Research Articles on NTR2

Similar Products

Product Notes

The NTR2 ntsr2 (Catalog #AAA5300533) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's NTR2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunofluorescence (IF), ELISA (EIA). WB: 1:500-1:1000 IF: 1:100-1:500 ELISA: 1:40000. Researchers should empirically determine the suitability of the NTR2 ntsr2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NTR2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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