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Rabbit anti-Human NSD2 Polyclonal Antibody | anti-NSD2 antibody

NSD2 Antibody, HRP conjugated

Gene Names
NSD2; WHS; TRX5; KMT3F; KMT3G; MMSET; WHSC1; REIIBP
Reactivity
Human
Applications
ELISA
Purity
>95%, Protein G purified
Synonyms
NSD2; Polyclonal Antibody; NSD2 Antibody; HRP conjugated; Histone-lysine N-methyltransferase NSD2; Multiple myeloma SET domain-containing protein; MMSET; Nuclear SET domain-containing protein 2; Protein trithorax-5; Wolf-Hirschhorn syndrome candidate 1 protein; anti-NSD2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Sequence Length
1365
Applicable Applications for anti-NSD2 antibody
ELISA (EIA)
Immunogen
Recombinant Human Histone-lysine N-methyltransferase NSD2 protein (1-44AA)
Conjugation
HRP
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.
Related Product Information for anti-NSD2 antibody
Histone methyltransferase with histone H3 'Lys-27' (H3K27me) methyltransferase activity. Isoform 2 may act as a transcription regulator that binds DNA and suppresses IL5 transcription through HDAC recruitment.
Product Categories/Family for anti-NSD2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
30,199 Da
NCBI Official Full Name
histone-lysine N-methyltransferase NSD2 isoform 1
NCBI Official Synonym Full Names
nuclear receptor binding SET domain protein 2
NCBI Official Symbol
NSD2
NCBI Official Synonym Symbols
WHS; TRX5; KMT3F; KMT3G; MMSET; WHSC1; REIIBP
NCBI Protein Information
histone-lysine N-methyltransferase NSD2
UniProt Protein Name
Histone-lysine N-methyltransferase NSD2
UniProt Gene Name
NSD2
UniProt Synonym Gene Names
MMSET

NCBI Description

This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t(4;14)(p16.3;q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences. [provided by RefSeq, Jul 2008]

Uniprot Description

Histone methyltransferase with histone H3 'Lys-27' (H3K27me) methyltransferase activity. Isoform 2 may act as a transcription regulator that binds DNA and suppresses IL5 transcription through HDAC recruitment.

Research Articles on NSD2

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Product Notes

The NSD2 nsd2 (Catalog #AAA7108148) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NSD2 Antibody, HRP conjugated reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NSD2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the NSD2 nsd2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NSD2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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