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Western Blot (WB) (All lanes : Anti-NQO2 Antibody (N-Term) at 1:2000 dilutionLane 1: 293T/17 whole cell lysateLane 2: Hela whole cell lysateLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.Predicted band size : 26 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Rabbit anti-Human NQO2 Polyclonal Antibody | anti-NQO2 antibody

NQO2 Antibody (N-Term)

Gene Names
NQO2; QR2; DHQV; DIA6; NMOR2
Reactivity
Human
Applications
Western Blot
Synonyms
NQO2; Polyclonal Antibody; NQO2 Antibody (N-Term); Purified Rabbit Polyclonal Antibody (Pab); Ribosyldihydronicotinamide dehydrogenase [quinone]; NRH dehydrogenase [quinone] 2; NRH:quinone oxidoreductase 2; Quinone reductase 2; QR2; NMOR2; anti-NQO2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Ig
Specificity
This NQO2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 21-52 amino acids from human NQO2.
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Sequence Length
231
Applicable Applications for anti-NQO2 antibody
Western Blot (WB)
Application Notes
WB ~~ 1:2000
Antigen Source
Human
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(All lanes : Anti-NQO2 Antibody (N-Term) at 1:2000 dilutionLane 1: 293T/17 whole cell lysateLane 2: Hela whole cell lysateLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.Predicted band size : 26 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Western Blot (WB) (All lanes : Anti-NQO2 Antibody (N-Term) at 1:2000 dilutionLane 1: 293T/17 whole cell lysateLane 2: Hela whole cell lysateLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.Predicted band size : 26 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Related Product Information for anti-NQO2 antibody
The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.
Product Categories/Family for anti-NQO2 antibody
References
Jaiswal A.K.,et al.Biochemistry 29:1899-1906(1990). Jaiswal A.K.,et al.J. Biol. Chem. 269:14502-14508(1994). Iida A.,et al.Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases. Ota T.,et al.Nat. Genet. 36:40-45(2004). Mungall A.J.,et al.Nature 425:805-811(2003).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
25919
NCBI Official Full Name
ribosyldihydronicotinamide dehydrogenase
NCBI Official Synonym Full Names
NAD(P)H dehydrogenase, quinone 2
NCBI Official Symbol
NQO2
NCBI Official Synonym Symbols
QR2; DHQV; DIA6; NMOR2
NCBI Protein Information
ribosyldihydronicotinamide dehydrogenase [quinone]
UniProt Protein Name
Ribosyldihydronicotinamide dehydrogenase [quinone]
UniProt Gene Name
NQO2
UniProt Synonym Gene Names
NMOR2; QR2
UniProt Entry Name
NQO2_HUMAN

NCBI Description

This gene encodes a member of the thioredoxin family of enzymes. It is a cytosolic and ubiquitously expressed flavoprotein that catalyzes the two-electron reduction of quinone substrates and uses dihydronicotinamide riboside as a reducing coenzyme. Mutations in this gene have been associated with neurodegenerative diseases and several cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]

Uniprot Description

NQO2: The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. Belongs to the NAD(P)H dehydrogenase (quinone) family.

Protein type: EC 1.10.99.2; Oxidoreductase

Chromosomal Location of Human Ortholog: 6p25.2

Cellular Component: nucleoplasm; cytoplasm

Molecular Function: protein binding; electron carrier activity; NADPH dehydrogenase (quinone) activity; metal ion binding

Biological Process: memory

Disease: Breast Cancer

Research Articles on NQO2

Similar Products

Product Notes

The NQO2 nqo2 (Catalog #AAA9215898) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NQO2 Antibody (N-Term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NQO2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB ~~ 1:2000. Researchers should empirically determine the suitability of the NQO2 nqo2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NQO2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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