Immunohistochemistry (IHC)
(Anti-NPTX1 / NP1 antibody IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Goat NPTX1 / NP1 Polyclonal Antibody | anti-NPTX1 antibody
Goat Polyclonal to Human NPTX1 / NP1
Gene Names
NPTX1; NP1
Reactivity
Gibbon, Chimpanzee, Human, Monkey
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Immunoaffinity Purified
Synonyms
NPTX1 / NP1; Polyclonal Antibody; Goat Polyclonal to Human NPTX1 / NP1; Anti-NPTX1 / NP1 Antibody (aa197-211) IHC-plus; NPTX1; Neuronal pentraxin-1; Neuronal pentraxin I; NP-I; NP1; Human NPTX1; anti-NPTX1 antibody
Host
Goat
Reactivity
Gibbon, Chimpanzee, Human, Monkey
Clonality
Polyclonal
Specificity
Human NPTX1 / NP1
Purity/Purification
Immunoaffinity Purified
Form/Format
Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Concentration
0.5 mg/ml (varies by lot)
Sequence Length
432
Applicable Applications for anti-NPTX1 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes
ELISA (1:128000), IHC-P (5 ug/ml), WB (1 - 3 ug/ml)
Usage: Peptide ELISA: antibody detection limit dilution 1:128000. Western blot: Approx 50kD band observed in Human Brain (Amygdala and Frontal Cortex) lysates (calculated MW of 47.1kD according to NP_002513.2). Recommended concentration: 1-3 ug/ml. Addition...
Usage: Peptide ELISA: antibody detection limit dilution 1:128000. Western blot: Approx 50kD band observed in Human Brain (Amygdala and Frontal Cortex) lysates (calculated MW of 47.1kD according to NP_002513.2). Recommended concentration: 1-3 ug/ml. Addition...
Target Species
Human
Immunogen Description
Synthetic peptide C-ERVKIETALTSLHQR from an internal region of human NPTX1 / NP1 (NP_002513.2). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey (100%); Ferret, Bovine, Elephant, Panda, Horse, Pig (93%).
Immunogen Type
Synthetic peptide
Immunogen
NPTX1 / NP1 antibody was raised against synthetic peptide C-ERVKIETALTSLHQR from an internal region of human NPTX1 / NP1 (NP_002513.2). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey (100%); Ferret, Bovine, Elephant, Panda, Horse, Pig (93%); Mouse, Rat, Guinea pig (87%); Rabbit, Chicken, Lizard (80%).
Antigen Modification
aa197-211
Preparation and Storage
Store at -20 degree C. Minimize freezing and thawing.
Immunohistochemistry (IHC)
(Anti-NPTX1 / NP1 antibody IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Immunohistochemistry (IHC)
(Anti-NPTX1 / NP1 antibody IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Western Blot (WB)
(NPTX1 antibody (1 ug/ml) staining of Human Frontal Cortex lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Western Blot (WB)
(NPTX1 antibody (1 ug/ml) staining of Human Frontal Cortex lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Related Product Information for anti-NPTX1 antibody
NPTX1 is a member of the neuronal pentraxin gene family. Neuronal pentraxin 1 is similar to the rat NP1 gene which encodes a binding protein for the snake venom toxin taipoxin. Human NPTX1 mRNA is exclusively localized to the nervous system.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
47,122 Da
NCBI Official Full Name
neuronal pentraxin-1
NCBI Official Synonym Full Names
neuronal pentraxin I
NCBI Official Symbol
NPTX1
NCBI Official Synonym Symbols
NP1
NCBI Protein Information
neuronal pentraxin-1; NP-I
UniProt Protein Name
Neuronal pentraxin-1
Protein Family
UniProt Gene Name
NPTX1
UniProt Synonym Gene Names
NP1; NP-I
UniProt Entry Name
NPTX1_HUMAN
NCBI Description
NPTX1 is a member of the neuronal pentraxin gene family. Neuronal pentraxin 1 is similar to the rat NP1 gene which encodes a binding protein for the snake venom toxin taipoxin. Human NPTX1 mRNA is exclusively localized to the nervous system. [provided by RefSeq, Jul 2008]
Uniprot Description
NPTX1: May mediate uptake of degraded synaptic material which could play an important role in synaptic remodeling. Can mediate the neuronal and glial uptake of the snake venom toxin taipoxin.
Protein type: Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 17q25.3
Cellular Component: transport vesicle; neuron projection; mitochondrion; plasma membrane
Molecular Function: metal ion binding
Biological Process: synaptic transmission; central nervous system development; transport; mitochondrial fragmentation during apoptosis; mitochondrial transport
Research Articles on NPTX1
Similar Products
Product Notes
The NPTX1 nptx1 (Catalog #AAA248350) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat Polyclonal to Human NPTX1 / NP1 reacts with Gibbon, Chimpanzee, Human, Monkey and may cross-react with other species as described in the data sheet. AAA Biotech's NPTX1 / NP1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA). ELISA (1:128000), IHC-P (5 ug/ml), WB (1 - 3 ug/ml) Usage: Peptide ELISA: antibody detection limit dilution 1:128000. Western blot: Approx 50kD band observed in Human Brain (Amygdala and Frontal Cortex) lysates (calculated MW of 47.1kD according to NP_002513.2). Recommended concentration: 1-3 ug/ml. Addition.. Researchers should empirically determine the suitability of the NPTX1 nptx1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NPTX1 / NP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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