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Western Blot (WB) (Western blot analysis of anti-NP1(Nptx1) Antibody (Center) in Jurkat cell line lysates (35ug/lane). NP1(arrow) was detected using the purified Pab.)

Rabbit anti-Human NPTX1 Polyclonal Antibody | anti-NPTX1 antibody

NPTX1, ID (NP1, Neuronal Pentraxin I, NP-I, 47kD Taipoxin-binding Protein)

Gene Names
NPTX1; NP1
Reactivity
Human
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Affinity Purified
Purified by Protein G affinity chromatography.
Synonyms
NPTX1; Polyclonal Antibody; ID (NP1; Neuronal Pentraxin I; NP-I; 47kD Taipoxin-binding Protein); Anti -NPTX1; anti-NPTX1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human NP1.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Form/Format
Supplied as a liquid in PBS, 0.09% sodium azide.
Applicable Applications for anti-NPTX1 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Suitable for use in ELISA, Western Blot, and Immunohistochemistry.
Dilution: ELISA: 1:1,000
Western Blot: 1:50-1:100
Immunohistochemistry: 1:50-1:100
Immunogen
Synthetic peptide selected from the Center region of rat NP1 (KLH).
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western blot analysis of anti-NP1(Nptx1) Antibody (Center) in Jurkat cell line lysates (35ug/lane). NP1(arrow) was detected using the purified Pab.)

Western Blot (WB) (Western blot analysis of anti-NP1(Nptx1) Antibody (Center) in Jurkat cell line lysates (35ug/lane). NP1(arrow) was detected using the purified Pab.)

Immunohistochemistry (IHC)

(Formalin-fixed and paraffin-embedded human breast carcinoma reacted with anti-NP1(Nptx1) Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)

Immunohistochemistry (IHC) (Formalin-fixed and paraffin-embedded human breast carcinoma reacted with anti-NP1(Nptx1) Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)

Immunohistochemistry (IHC)

(Formalin-fixed and paraffin-embedded human brain tissue reacted with NP1(Nptx1) Antibody (Center) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)

Immunohistochemistry (IHC) (Formalin-fixed and paraffin-embedded human brain tissue reacted with NP1(Nptx1) Antibody (Center) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
Related Product Information for anti-NPTX1 antibody
NPTX1 is a member of the neuronal pentraxin family. Human neuronal pentraxin 1 is similar to rat NP1 which is a binding protein for the snake venom toxin taipoxin.
Product Categories/Family for anti-NPTX1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
47,122 Da
NCBI Official Full Name
neuronal pentraxin-1
NCBI Official Synonym Full Names
neuronal pentraxin I
NCBI Official Symbol
NPTX1
NCBI Official Synonym Symbols
NP1
NCBI Protein Information
neuronal pentraxin-1; NP-I
UniProt Protein Name
Neuronal pentraxin-1
Protein Family
UniProt Gene Name
NPTX1
UniProt Synonym Gene Names
NP1; NP-I
UniProt Entry Name
NPTX1_HUMAN

NCBI Description

NPTX1 is a member of the neuronal pentraxin gene family. Neuronal pentraxin 1 is similar to the rat NP1 gene which encodes a binding protein for the snake venom toxin taipoxin. Human NPTX1 mRNA is exclusively localized to the nervous system. [provided by RefSeq, Jul 2008]

Uniprot Description

NPTX1: May mediate uptake of degraded synaptic material which could play an important role in synaptic remodeling. Can mediate the neuronal and glial uptake of the snake venom toxin taipoxin.

Protein type: Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 17q25.3

Cellular Component: transport vesicle; neuron projection; mitochondrion; plasma membrane

Molecular Function: metal ion binding

Biological Process: synaptic transmission; central nervous system development; transport; mitochondrial fragmentation during apoptosis; mitochondrial transport

Research Articles on NPTX1

Similar Products

Product Notes

The NPTX1 nptx1 (Catalog #AAA630009) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NPTX1, ID (NP1, Neuronal Pentraxin I, NP-I, 47kD Taipoxin-binding Protein) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NPTX1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC). Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Dilution: ELISA: 1:1,000 Western Blot: 1:50-1:100 Immunohistochemistry: 1:50-1:100. Researchers should empirically determine the suitability of the NPTX1 nptx1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NPTX1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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