Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

Western Blot (WB) (Western blot analysis of extracts of Rat plasma using NPFF Polyclonal Antibody at dilution of 1:500.)

Rabbit anti-Human, Rat NPFF Polyclonal Antibody | anti-NPFF antibody

NPFF Polyclonal Antibody

Gene Names
NPFF; FMRFAL
Reactivity
Human, Rat
Applications
Western Blot
Purity
Affinity purification
Synonyms
NPFF; Polyclonal Antibody; NPFF Polyclonal Antibody; FMRFAL; anti-NPFF antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purification
Form/Format
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Concentration
1mg/mL (varies by lot)
Applicable Applications for anti-NPFF antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
Recombinant fusion protein of human NPFF (NP_0037081)
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of extracts of Rat plasma using NPFF Polyclonal Antibody at dilution of 1:500.)

Western Blot (WB) (Western blot analysis of extracts of Rat plasma using NPFF Polyclonal Antibody at dilution of 1:500.)
Related Product Information for anti-NPFF antibody
This gene encodes a member of the FMRFamide related peptide (FARP) family of neuropeptides. The encoded preproprotein is proteolytically processed to generate multiple amidated peptides. These peptides may play a role in the regulation of heart rate and blood pressure and the modulation of morphine-induced antinociception. Patients with hypertension exhibit decreased expression of the encoded protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Product Categories/Family for anti-NPFF antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
113
NCBI Official Full Name
Pro-FMRFamide-related neuropeptide FF
NCBI Official Synonym Full Names
neuropeptide FF-amide peptide precursor
NCBI Official Symbol
NPFF
NCBI Official Synonym Symbols
FMRFAL
NCBI Protein Information
pro-FMRFamide-related neuropeptide FF
UniProt Protein Name
Pro-FMRFamide-related neuropeptide FF
UniProt Gene Name
NPFF
UniProt Synonym Gene Names
NPSF; NPFF; NPAF
UniProt Entry Name
NPFF_HUMAN

NCBI Description

FMFRamide-related protein precursor plays a role in the regulation of heart rate and blood pressure and the modulation of morphine-induced antinociception. FMRFAL encodes a preproprotein which is cleaved to form two active peptides with similar function. [provided by RefSeq, Jul 2008]

Uniprot Description

NPFF: Morphine modulating peptides. Have wide-ranging physiologic effects, including the modulation of morphine-induced analgesia, elevation of arterial blood pressure, and increased somatostatin secretion from the pancreas. Neuropeptide FF potentiates and sensitizes ASIC1 and ASIC3 channels. Belongs to the FARP (FMRFamide related peptide) family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 12q13.13

Cellular Component: extracellular space; dendrite; extracellular region; perikaryon; nerve terminal; vesicle

Molecular Function: neuropeptide hormone activity; G-protein-coupled receptor binding; receptor binding

Biological Process: response to drug; negative regulation of heart rate; maternal process involved in pregnancy; response to morphine; negative regulation of appetite; negative regulation of insulin secretion; vasopressin secretion; synaptic transmission; elevation of cytosolic calcium ion concentration; neuropeptide signaling pathway; spinal cord development; regulation of sensory perception of pain; regulation of excitatory postsynaptic membrane potential; positive regulation of blood pressure; acute inflammatory response to antigenic stimulus

Research Articles on NPFF

Similar Products

Product Notes

The NPFF npff (Catalog #AAA2566642) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NPFF Polyclonal Antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's NPFF can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the NPFF npff for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NPFF, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.