Rabbit anti-Human NP-5 Polyclonal Antibody | anti-LOC100009136 antibody
NP-5 (alpha Defensin-5, HNP-5) (FITC)
Gene Names
LOC100009136; CS-6; NP-5
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Affinity PurifiedPurified by immunoaffinity chromatography.
Synonyms
NP-5; Polyclonal Antibody; NP-5 (alpha Defensin-5; HNP-5) (FITC); Anti -NP-5 (alpha Defensin-5; anti-LOC100009136 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human alpha defensin-5. No significant homology exists with other alpha-defensins.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.5, 0.1% BSA. No preservative added. Conjugated to Fluorescein isothiocyanate (FITC).
Applicable Applications for anti-LOC100009136 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in ELISA and Western Blot., Recommended Dilution:, Western Blot: 1:100-1:500 using ECL., ELISA: 1:100-1:500, Optimal dilutions to be determined by the researcher., Control Peptide: N5378-07., Storage and Stability:, Store at 4 degree C. Do Not Freeze. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. FITC conjugates are sensitive to light.
Immunogen
A synthetic17-aa peptide sequence near the C-terminus of human mature alpha defensin-5 (KLH coupled).
Preparation and Storage
4 degree C Do Not Freeze
Related Product Information for anti-LOC100009136 antibody
Defensins are a large family of broad-spectrum antimicrobial peptides, identified originally in leukocytes of rabbits and humans. Defensins, cationic/polar peptides (30-35aa; 3-4kD), are distinguished by a conserved tri-disulfides and a largely beta-sheet structure. Defensins, expressed at the cell surface, have been hypothesized to function as a biochemical barrier against microbial infection by inhibiting colonization of the epithelium by wide range of pathogenic microorganisms. In leukocytes, these peptides are stored in cytoplasmic granules and are released into phagolysosomes where they contribute to the killing of engulfed microorganisms. The genes encoding human alpha and beta-defensins are clustered in a contiguous segment of chromosome 8p23. Defensins are classified into two families designated alpha and beta based on distinctive, although similar, tri-disulfide linkages in the peptides. beta-defensins are slightly larger and differ in the position and arrangement of 3 disulfides. In humans, six alpha-defensin (cryptidins), HD 1-6 (HD1-4 are also known as HNP1-4 for Human Neutrophil Peptides), and two beta-defensins, HBD-1 and HBD-2, have been identified.
Product Categories/Family for anti-LOC100009136 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
10,122 Da
NCBI Official Full Name
neutrophil antibiotic peptide NP-5
NCBI Official Symbol
LOC100009136
NCBI Official Synonym Symbols
CS-6; NP-5
NCBI Protein Information
neutrophil antibiotic peptide NP-5; defensin np-5; corticostatin CS-6; microbicidal peptide NP-5
UniProt Protein Name
Neutrophil antibiotic peptide NP-5
UniProt Entry Name
DEF6_RABIT
Uniprot Description
Function: Microbicidal activity.
Subcellular location: Secreted.
Sequence similarities: Belongs to the alpha-defensin family.
Similar Products
Product Notes
The LOC100009136 (Catalog #AAA612194) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NP-5 (alpha Defensin-5, HNP-5) (FITC) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NP-5 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in ELISA and Western Blot., Recommended Dilution:, Western Blot: 1:100-1:500 using ECL., ELISA: 1:100-1:500, Optimal dilutions to be determined by the researcher., Control Peptide: N5378-07., Storage and Stability:, Store at 4 degree C. Do Not Freeze. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. FITC conjugates are sensitive to light. Researchers should empirically determine the suitability of the LOC100009136 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NP-5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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